PROFESSIONAL EXPERIENCE:

1991-1992:     Research Technician (Part-Time) of Dr. Robert Beesley, Department
                          of Physiology, University of Oklahoma Health Sciences Center,                           Oklahoma City, OK.
1994-1997:     Research Associate, Department of Neuropharmacology, The Scripps                           Research Institute, La Jolla, CA.
1997-1999:     Senior Research Associate, Department of Neuropharmacology, The                           Scripps Research Institute, La Jolla, CA.
1999-2004:      Assistant Professor, Department of Neuropharmacology, The Scripps                            Research Institute, La Jolla, CA.
2004-2007:      Dallas and Mary Clark Fellow in Human Neurophysiology, Brain                            Research and Treatment Center, Division of Neurology ScrippsClinic,                            La Jolla, CA.
2004-2007:      Adjunct Assistant Professor, Molecular and Integrative Neuroscience                            Department, The Scripps Research Institute, La Jolla, CA.
2007-Present: Staff Scientist, Molecular and Integrative Neuroscience Department,
                           The Scripps Research Institute, La Jolla, CA.

AWARDS & HONORS:
1986:           Travel Fellowship: Society for Neuroscience 1986 Annual Meeting,                       November 9-14 in Washington, D.C.  Sponsored by the Society for                       Neuroscience.
1985-1986: Graduate and Professional Opportunity Program Fellowship:                       Pre-Doctoral  Training (Doctoral Program in Biological Psychology),                       University of Oklahoma Health Sciences Center.
1986-1989: Ford Foundation Minority Pre-Doctoral Fellowship: National Research                       Council, Washington, D.C. (Doctoral Program in Biological Psychology),                       University of Oklahoma Health Sciences Center.
1989-1992: Patricia Roberts Harris Fellow: University of Oklahoma Health Sciences                       Center, Oklahoma City, OK
1991:            Travel Fellowship: the FASEB 1991 Annual Meeting, April 21-25 in                        Atlanta, GA.  Sponsored by the American Physiological Society.
1994-1998: Research Supplement for underrepresented minorities: National                       Institute on Drug Abuse Grant, P.I.: Steven J. Henriksen, Ph.D. Grant                       Title: "Electrophysiological Substrates of Opioid Abuse".
1996:            Travel Fellowship: "Minority Fellows Forum: Neuroscience Research in                        Drugs of Abuse", November 19 in Washington, D.C.  Sponsored by the                        National Institute on Drug Abuse (NIDA).
1996:            Travel Fellowship: College on Problems of Drug Dependence (CPDD)                        Annual Scientific Meeting, June 22-27 in San Juan, P.R.  Sponsored by                        The College on Problems of Drug Dependence .
1997:             Travel Fellowship: FASEB Summer Conference on Drug Abuse entitled:                         "The Role of Neural and Behavioral Plasticity in Chronic Drug Abuse",                         August 10-15 in Copper Mountain, Colorado.  Sponsored by FASEB and                         The National Institute on Drug Abuse (NIDA).

PROFESSIONAL SOCIETIES:
American Psychological Society
Society for Neuroscience
Society for Advancement of Chicanos and Native Americans in Science
Pi Gamma Mu, International Honor Society in Social Science, Puerto Rico Alpha Chapter, Catholic University of Puerto Rico, 1983.

PEER-REVIEWED MANUSCRIPTS:
1. Michaelis RC, Holohean AM, Criado JR, Harland R, Hunter GA, Holloway FA: The Chlordiazepoxide/Pentylenetetrazol discrimination: characterization of drug interactions and homeostatic responses to drug challenges. Psychopharmacology 96: 15-20, 1988.

2. Gauvin DV, Harland RD, Criado JR, Michaelis RC, Holloway FA: The discriminative stimulus properties of ethanol and acute ethanol withdrawal states in rats. Drug Alcohol Depend 24: 103-113, 1989.

3. Gauvin DV, Criado JR, Moore KM, Holloway FA: Potentiation of cocaine's discriminative effects by caffeine: A time-effect analysis. Pharmacol Biochem Behav 36: 195-197, 1990.

4. Holloway FA, Michaelis RC, Harland RD, Criado JR, Gauvin DV: Tolerance to Ethanol's Effects on Operant Performance in Rats: Role of Number and Pattern of Intoxicated Practice Opportunities. Psychopharmacology  109:112-120, 1992.

5. Criado JR, Steffensen SC, Henriksen SJ: Ethanol acts via the ventral tegmental area to influence hippocampal physiology. Synapse 17:84-96, 1994.

6. de Lecea L, Soriano E, Criado JR, Steffensen SC, Henriksen SJ, Sutcliffe JG: Transcripts encoding a neural membrane CD26 peptidase-like protein are stimulated by synaptic activity. Mol Brain Res 25:286-296, 1994.

7. Prospéro-García O, Criado JR, Henriksen SJ: Pharmacology of ethanol and glutamate antagonists on rodent sleep: a comparative study. Pharmacol Biochem Behav 49(2):413-416, 1994.

8. Criado JR, Thies R: Acute effects of ethanol on recurrent inhibitory circuits of CA1 neurons in vivo. Alcohol 11(6):533-538, 1994.

9. Criado JR, Lee RS, Berg G, Henriksen SJ: Sensitivity of nucleus accumbens neurons in vivo  to intoxicating doses of ethanol. Alcohol Clin Exp Res 19(1):164-169, 1995.

10. de Lecea L, Criado JR, Prospéro-Garcia O, Gautvik KM, Schweitzer P, Danielson PE, Dunlop CLM, Siggins GR, Henriksen SJ and Sutcliffe JG: Cortistatin, a cortical neuropeptide with neuronal depressant and sleep-modulating properties. Nature  381:242-245, 1996.

11. Criado JR, Steffensen SC, Henriksen SJ: Microelectrophoretic application of SCH-23390 into the lateral septal nucleus blocks ethanol-induced suppression of LTP, in vivo, in the adult rodent hippocampus Brain Res 716:192-196, 1996.

12. Ryabinin AE, Criado JR, Henriksen SJ, Bloom FE, Wilson MC: Differential sensitivity of c-Fos expression in hippocampus and other brain regions to moderate and low doses of alcohol. Mol Psychiatry 2:32-43, 1997.

13. Criado JR, Lee RS, Berg GI, Henriksen SJ: Ethanol inhibits single-unit responses in the nucleus accumbens evoked by stimulation of the basolateral nucleus of the amygdala. Alcohol Clin Exp Res 21(2):368-374, 1997.

14. de Lecea L, del Rio JA, Criado JR, Alcántara S, Morales M, Henriksen SJ, Soriano E, Sutcliffe JG: Cortistatin is expressed in a distinct subset of cortical interneurons. J Neurosci 17(15): 5868-5880, 1997.

15. Morales M, Criado JR, Sanna PP, Henriksen SJ, Bloom FE: Acute ethanol activates GABAergic neurons of the central nucleus of the amygdala. Brain Res 798: 333-336, 1998.

16. de Lecea L, Criado JR, Rivera S, Wen W, Soriano E, Henriksen S, Taylor S, Gall C, Sutcliffe JG: Endogenous protein kinase A inhibitor (PKIa) modulates synaptic activity. J Neurosci Res 53: 269-278, 1998.

17. Lee RS, Criado JR, Koob GF, Henriksen SJ: Cellular responses of nucleus accumbens neurons to opiate-seeking behavior: I. Sustained responding during heroin self-administration. Synapse 33: 49-58, 1999.

18. Criado JR, Li H, Jiang X, Spina M, Huitrón-Reséndiz S, Liapakis G, Calbet M, Siehler S, Henriksen SJ, Koob GF, Hoyer D, Sutcliffe JG, Goodman MH, de Lecea L: Structural and compositional determinants of cortistatin activity. J Neurosci Res 56: 611-619, 1999.

19. Gallegos RA, Lee RS, Criado JR, Henriksen SJ, Steffensen SC: Adaptive responses of g-Aminobutyric acid neurons in the ventral tegmental area to chronic ethanol.  J Pharmacol Exp Therapeutics 291:1045-1053, 1999.

20. Criado JR, Morales M: Ethanol induces c-fos immunoreactivity in pro-enkephalin expressing neurons of the central nucleus of the amygdala. Brain Res 861:173-177, 2000.

21. Criado JR, Gombart LM, Huitrón-Reséndiz S, Henriksen SJ: Neuroadaptations in dentate gyrus function following repeated methamphetamine administration. Synapse 37:163-166, 2000.

22. Steffensen SC, Nie Z, Criado JR, Siggins GR, Henriksen SJ: Ethanol inhibition of NMDA responses by activation of presynaptic GABAb receptors. J Pharmacol Exp Therapeutics 294:637-647, 2000.

23. Sanchez-Alavez M, Criado JR, Gomez-Chavarin M, Jimenez-Anguiano A, Navarro L, Diaz-Ruiz O, Galicia O, Sanchez-Narvaez F, Murillo-Rodriguez E, Henriksen SJ, Elder JH, Prospero-Garcia O: HIV- and FIV-derived gp120 alter spatial memory, LTP, and sleep in rats. Neurobiol Dis 7(4):384-394, 2000.

24. Bourgin P, Huitron-Resendiz S, Spier AD, Fabre V, Morte B, Criado JR, Sutcliffe JG, Henriksen SJ, de Lecea L: Hypocretin-1 modulates rapid eye movement sleep through activation of locus coeruleus neurons. J Neurosci 20(20):7760-7765, 2000.

25. Giacchino JL, Criado JR, Games D, Henriksen, SJ: In vivo synaptic transmission in young and aged amyloid precursor protein transgenic mice.  Brain Res 876(1-2):185-190, 2000.

26. Thomas EA, Sautkulis LN, Criado JR, Games D, JG Sutcliffe: Apolipoprotein D mRNA expression is elevated in aged PDAPP transgenic mice. J Neurochem 79: 1059-1064, 2001.

27. Huitrón-Reséndiz S, Sánchez-Alavez M, Gallegos RA, Berg G, Battenberg E, Giacchino JL, Games D, Henriksen SJ, Criado JR: Age-independent and age-related functional deficits in PDAPP mice involve alterations in visuospatial learning, sleep-wake states, thermoregulation and motor activity. Brain Res 928: 126-137, 2002.

28. Sánchez-Alavez M, Gallegos RA, Kalafut MA, Games D, Henriksen SJ, Criado JR: Loss of medial septal modulation of dentate gyrus physiology in young mice overexpressing human ß-amyloid precursor protein. Neurosci Lett 330:45-48, 2002.

29. Samland H, Huitrón-Resendiz S, Masliah E,  Criado JR, Henriksen SJ, Campbell IL: Profound increase in sensitivity to glutamatergic but not cholinergic agonist induced seizures in transgenic mice with astrocyte production of IL-6. J Neurosci Res 73:176-187, 2003.

30. Sánchez-Alavez M, Gombart LM, Huitrón-Reséndiz S, Carr JR, Wills DN, Berg G, Campbell IL, Gauvin DV, Henriksen SJ, Criado JR: Physiological and behavioral effects of methamphetamine in a mouse model of endotoxemia: a preliminary study. Pharmacol Biochem Behav 77:365-370, 2004.

31. Solforosi L, Criado JR, McGavern D, Wirz S, Sanchez-Alavez M, DeGiorgio LA, Volpe BT, Wiseman E, Abalos G, Masliah M, Oldstone MB, Conti B, Williamson A. Crosslinking cellular prion protein triggers neuronal apoptosis in vivo. Science 303: 1514-1516, 2004; published online 29 January 2004 (10.1126/science.1094273).

32. Winsky-Sommerer R, Spier A, Fabre V, de Lecea L, Criado JR: Overexpression of the human ß-amyloid precursor protein downregulates cortistatin mRNA in PDAPP mice. Brain Research 1023:157-162, 2004.

33. Criado JR, Sánchez-Alavez M, Conti B, Giacchino JL, Wills DN, Henriksen SJ, Manson JC, Chesebro B, Oldstone MBA: Mice devoid of prion protein have cognitive deficits that are rescued by reconstitution of PrP in neurons. Neurobiol Dis 19:255-265, 2005.

34. Sánchez-Alavez M, Huitrón-Reséndiz S, Criado JR: Sleep/wake states in transgenic mouse models overexpressing the human ß-amyloid precursor protein. Am J Alzheimer's Dis Other Dementias 20:87-90, 2005.

35. Huitrón-Resendiz S, Clark SD, Sánchez-Alavez M, Tyler C, Nothacker H-P, Civelli O, Leonard CS, Henriksen SJ, Criado JR, de Lecea L: Urotensin II modulates REM sleep through activation of brainstem cholinergic neurons. J Neurosci 25: 5465-5474, 2005.

36. Tallent MK, Fabre V, Qiu C, Calbet M, Lamp T, Baratta MV, Suzuki C, Levy CL, Siggins GR, Henriksen SJ, Criado JR, Roberts A, de Lecea L: Cortistatin overexpression in transgenic mice produces deficits in synaptic plasticity and learning. Mol CellNeurosci 30(3):465-475, 2005.

37. Polich J, Criado JR: Neuropsychology and Neuropharmacology of P3a and P3b. Internat J Psychophysiol60(2):172-185, 2006.

38. Amo C, Criado JR, Otis SM: MEG Recording from secondary motor areas during motor imagined movements.  Arquivos de Neuro-Psiquiatria 64(2):394-397, 2006.

39. Sánchez-Alavez M, Chan L, Mattson MP, Criado JR: Electrophysiological and cerebrovascular effects of a-secretase-derived form of amyloid precursor protein in young adult and middle-aged rats. Brain Res 1131(1):112-117, 2007.

40. Ehlers CL, Phillips E, Finnerman G, Gilder D, Lau P, Criado JR: P3 components and adolescent binge drinking in Southwest California Indians. Neurotoxicol Teratol 29(1):153-163, 2007.

41. Criado JR, Amo C, Quint P, Kurelowech L, Otis SM. Using magnetoencephalography to study patterns of brain magnetic activity in Alzheimer's disease. Am J Alzheimer's Dis Other Dementias 21(6):416-423, 2007.