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The Disney Lab

Software

Both the RNA-PSP and Chem-PSP software packages are available for download by using the below links.

1. Descriptions of RNA-PSP can be found in these publications: Paul DJ, Seedhouse SJ, and Disney MD.  Two-dimensional combinatorial screening and the RNA Privileged Space Predictor (RNA-PSP) efficiently identify aminoglycoside-RNA hairpin loop interactions. Nucleic Acids Research, (2009), 37, 5894-5907; Velagapudi SP, Seedhouse SJ, Disney MD. Structure-activity relationships through sequencing (StARTS) defines optimal and suboptimal RNA motif targets for small molecules.  Angewandte Chemie International Edition, English (2010), 49, 3816-3818.

Link to download both versions of RNA-PSP

2. Description of Chem-PSP can be found in this publication:  Bioorganic Medicinal Chemistry Letters (2010), 20, 1338-1343.

Link to download Chem-PSP

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