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 Publications
In the order by year:

Wan, H., Sorrell, E.M., Song, H., Hossain, M.J., Ramirez-Nieto, G., Monne, I., Stevens, J., Cattoli, G., Capua, I., Chen, L-M., Donis, R.O., Busch, J., Paulson, J.C., Brockwell, C., Webby, R., Blanco, J., Al-Natour, M.Q., Perez, D.R. (2008) Replication and transmission of H9N2 influenza viruses in ferrets: evaluation of pandemic potential. PLoS ONE. 3(8):e2923.

Stevens, J., Blixt, O., Chen, L-M., Donis, R., Paulson, J.C., and Wilson, I.A. (2008) Recent avian H5N1 viruses exhibit increased propensity for acquiring human receptor specificity. J. Mol. Biol. 381(5):1382-94.

O'Reilly, M.K., Collins, B.E., Han, S., Liao, L., Rillahan, C., Kitov, P.I., Bundle, D.R., and Paulson, J.C. (2008) Bi-functional CD22 ligands use multimeric immunoglobulins as protein scaffolds in assembly of immune complexes on B cells. J. Am. Chem. Soc. 130(24):7736-45.

Belser, J.A., Blixt, O., Chen, L-M., Pappas, C., Maines, T.R.,Hoeven, N.V., Donis, R., Busch, J., McBride, R., Paulson, J.C., Katz, J.M., and Tumpey, T.M. (2008) Contemporary North American influenza H7 viruses possess human receptor specificity: Implications for virus transmissibility. Proc. Natl. Acad. Sci. USA. 105(21):7558-63.

Blixt,O., Han, S., Liao, L., Zeng, Y. Hoffmann, J., Futakawa, S., and Paulson, J.C. (2008) Sialoside analogue arrays for rapid identification of high affinity siglec ligands. J. Am. Chem. Soc. 130(21):6680-81.

Anthony, R.M., Nimmerjahn, F., Ashline, D.J., Reinhold, R.N., Paulson, J. C., and Ravetch, J.V. (2008) Recapitulation of IVIG anti-inflammatory activity with a recombinant IgG Fc. Science. 320(5874):373-76.

Kaltgrad, E., O'Reilly, M.K., Liao, L., Han, S., Paulson, J.C., and Finn, M.G. (2008) On-virus construction of polyvalent glycan ligands for cell-surface receptors. J. Am. Chem. Soc. 130(14):4578-9.

Nicholls, J.M., Aschenbrenner, L.M., Paulson, J.C., Campbell, E.R., Malakhov, M.P., Wurtman, D.F., Yu, M. and Fang, F. (2008) Comment on: Concerns of using sialidase fusion protein as an experimental drug to combat seasonal and pandemic influenza. J. Antimicrob. Chemother. 62(2):426-8.

Packer, N.H, von der Lieth, C.W., Aoki-Kinoshita, K.F., Lebrilla, C.B., Paulson, J.C., Raman, R., Rudd, P., Sasisekharan, R., Taniguchi, N., York, W.S. (2008) Frontiers in glycomics: Bioinformatics and biomarkers in disease An NIH White Paper prepared from discussions by the focus groups at a workshop on the NIH campus, Bethesda MD (September 11-13, 2006). Proteomics. 1:8-20..

Paulson, J.C. (2007) Innate immune response triggers lupus-like autoimmune disease. Cell. 130:589-591.

Tateno, H., Li, H., Schur, M.J., Bovin, N., Crocker, P.R., Wakarchuk, W.E., and Paulson, J.C. (2007) Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F reflect roles in cell-signaling and innate immunity. Mol. Cell. Biol. 27:5699-710.

Glaser, L., Gina, Conenello, G., Paulson, J.C., and Palese, P. (2007) Effective replication of human influenza viruses in mice lacking a major a2,6 sialyltransferase. Virus Res. 126:9-18.

Crocker, P., Paulson, J.C., and Varki, A. (2007) Siglecs and their roles in the immune system. Nature Rev. Immunol. 4:255-66.

Han, S., Collins, B.E., and Paulson, J.C. (2007) Synthesis of 9-Substituted Sialic Acids As Probes for CD22-Ligand Interactions on B cells. A.V. Demchenko (ed), In Frontiers in Modern Carbohydrate Chemistry. ACS Symposium Series 960:2-14.

Taniguchi, N. and Paulson, J.C. (2007) Frontiers in glycomics; bioinformatics and biomarkers in disease. Proteomics, 7:1360-1363.

Stevens, J., Blixt, O., Paulson, J.C., and Wilson, I.A. (2006) Glycan microarray technologies: tools to survey host specificity of influenza viruses. Nat. Rev. Microbiol. 4:857-64.

Collins, B.E., Blixt, O., Han, S. Duong, B., Li, H., Nathan, J.K., Bovin, N., and Paulson, J.C. (2006) High-affinity ligand probes of CD22 overcome the threshold set by cis ligands to allow for binding, endocytosis, and killing of B cells. J. Immunol. 177:2994-3003.

Comelli, E.M., Sutton-Smtih, M., Yan, Q., Amado, M., Panico, M., Gilmartin, T., Whisenant, T., Lanigan, C.M., Head, S.R., Goldberg, D., Morris, H., Dell, A., and Paulson, J.C. (2006) Activation of murine CD4+ and CD8+ T lymphocytes leads to dramatic remodeling of N-linked glycans. J. Immunol. 177:2431-40.

Paulson, J.C., Blixt, O., and Collins, B.E. (2006) Sweet spots in functional glycomics. Nature Chem. Biol. 2:238-48

Stevens, J., Blixt, O., Tumpey, T.M., Taubenberger, J.K., Paulson, J.C., and Wilson, I.A. (2006) Structure and receptor specificity of the hemagglutinin from an H5N1 influenza virus. Science. 312:404-410.

Collins, B.E., Smith, B.A., Bengtson, P., and Paulson, J.C. (2006) Ablation of CD22 in ligand-deficient mice restores B cell receptor signaling. Nature Immunol. 7:199-206

Comelli, E.M., Head, S.R., Gilmartin, T., Whisenant, T., Haslam, S.M., North, S.J., Wong, N.K., Kudo, T., Narimatsu, H., Esko, J.D., Drickamer, K., Dell, A., and Paulson, J.C. (2006) A focused microarray approach to functional glycomics: transcriptional regulation of the glycome. Glycobiology. 16:117-131

Stevens, J., Blixt, O., Glaser, L., Taubenberger, J.K., Palese, P., Paulson, J.C., and Wilson, I.A. (2006) Glycan microarray analysis of the hemagglutinins from modern and pandemic influenza viruses reveals different receptor specificities. J. Mol. Biol. 355:1143-55.

Taniguchi, N., Nakamura, K., Narimatsu, H., von der Lieth, C.W., and Paulson, J.C. (2006) Human Disease Glycomics/Proteome Initiative Workshop and the 4th HUPO Annual Congress. Proteomics. 6:12-3.

Raman, R., Raguram, S., Venkataraman, G., Paulson, J.C. , and Sasisekharan, R. (2005) Glycomics: an integrated systems approach to structure-function relationships of glycans. Nature Methods 2:817-824

Tateno, H., Crocker, P. and Paulson, J.C. (2005) Mouse Siglec-F and Human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6'-Sulfo-Sialyl Lewis X as a preferred glycan ligand. Glycobiology. 15:1125-1135.

Han, S., Collins, B.E., Bengtson, P., and Paulson, J.C. (2005) Homomultimeric complexes of CD22 in B cells revealed by protein-glycan cross-linking. Nature Chem. Biol. 1:93-97

Blixt, O., Vasiliu, D., Allin, K., Jacobsen, N., Warnock, D., Razi, N., Paulson, J.C., Bernatchez, S., Gilbert, M., and Wakarchuk, W. (2005) Chemoenzymatic synthesis of 2-azidoethyl-ganglio-oligosaccharides GD3, GT3, GM2, GD2, GT2, GM1, and GD1a. Carbohydrate Research. 340:1963-72

Vyas, A.A., Blixt, O., Paulson, J.C., and Schnaar, R.L. (2005) Potent glycan inhibitors of myelin-associated glycoprotein enhance axon outgrowth in vitro. J. Biol. Chem. 280:16305-10

Goldberg, D., Sutton-Smith, M., Paulson, J.C., and Dell, A. (2005) Automatic annotation of matrix-assisted laser desorption/ionization N-glycan spectra. Proteomics. 5:865-875

Kitazume, S., Nakagawa, K., Oka, R., Tachida, Y., Ogawa, K., Luo, Y., Citron, M., Shitara, H., Taya, C., Yonekawa, H., Paulson, J.C., Miyoshi, E., Taniguchi, N., and Hashimoto, Y. (2005) In vivo cleavage of alpha 2,6-sialyltransferase by Alzheimer's beta -secretase. J. Biol. Chem. 280:8589-8595

Blixt, O., Head, S., Mondala, T., Scanlan, C., Huflejt, M.E., Alvarez, R., Bryan, M.C., Fazio, F., Calarese, D., Stevens, J., Razi, N., Stevens, D.J., Skehel, J.J., van Die, I., Burton, D.R., Wilson, I.A., Cummings, R., Bovin, N., Wong, C-H., and Paulson, J.C. (2004) Printed covalent glycan array for ligand profiling of diverse glycan binding proteins. Proc. Natl. Acad. Sci. USA 101:17033-17038

Collins, B.E. and Paulson, J.C. (2004) Cell surface biology mediated by low affinity multivalent protein-glycan interactions. Curr. Opin. Chem. Biol. 8:617-625.

Ikehara, Y., Ikehara, S.K., and Paulson, J.C. (2004) Negative regulation of T cell receptor signaling by Siglec-7 (p70/AIRM) and Siglec-9. J. Biol. Chem. 279:43117-43125

Amado, M., Qi, Y., Comelli, E.M., Collins, B. and Paulson, J.C. (2004) PNA high phenotype of activated CD8+ T cells results from de novo synthesis of CD45 glycans. J. Biol. Chem. 279:36689-97.

Collins, B. E., Blixt, O., DeSieno, A. R., Bovin, N., Marth, J. D., and Paulson, J.C. (2004) Masking of CD22 by cis ligands does not prevent redistribution of CD22 to sites of cell contact. Proc. Natl. Acad. Sci. USA 101:6104-6109.

Bryan, M.C., Fazio, F., Lee, H-K., Huang, C-Y., Chang, A., Best, M.D., Calarese, D.A., Blixt, O., Paulson, J.C., Burton, D., Wilson, I.A., and Wong, C-H. (2004) Covalent display of oligosaccharide arrays in microtiter plates. J. Amer. Chem. Soc. 126:8640-8641.

Shen, A., Go, E.P., Gamez, A., Apon, J.V., Fokin, V., Greig, M., Ventura, M., Crowell, J.E., Blixt, O., Paulson, J.C., Stevens, R.C., Finn, M.G., and Siuzdak, G. (2004) A mass spectrometry plate reader: monitoring enzyme activity and inhibition with a Desorption/Ionization on Silicon (DIOS) platform. Chem. Bio. Chem. 5:921-927

Blixt, O., Collins, B.E., Van Den Nieuwenhof, I.M., Crocker, P.R., and Paulson, J.C. (2003) Sialoside specificity of the siglec family assessed using novel multivalent probes: identification of potent inhibitors of myelin-associated glycoprotein. J. Biol. Chem. 278:31007-19.

Comelli, E. M., Amado, M., Lustig, S. R., and Paulson, J. C. (2003) Identification and expression of Neu4, a novel murine sialidase. Gene 321:155-161.

Blixt, O. and Paulson, J.C. (2003) Biocatalytic Preparation of N-Glycolylneuraminic Acid, Deaminoneuraminic Acid (KDN) and 9-Azido-9-deoxysialic Acid Oligosaccharides. Adv. Synth. Catal. 345:687-690.

Kalovidouris, S.A., Blixt, O., Nelson, A., Vidal, S., Turnbull, W.B, Paulson, J.C., and Stoddart, J.F. (2003) Chemically Defined Sialoside Scaffolds for Investigations with Sialic Acid Binding Proteins. J. Org. Chem. 68:8485-8493.

Danzer, C.P., Collins, B.E., Blixt, O., Paulson, J.C., and Nitschke, L. (2003) Transitional and marginal zone B cells have a high proportion of unmasked CD22: implications for BCR signaling. Int. Immunol. 15:1137-1147.

Zuber, C., Paulson, J.C., Toma, V., Winter, H.C., Goldstein, I.J., and Roth, J. (2003) Spatiotemporal expression patterns of sialoglycoconjugates during nephron morphogenesis and their regional and cell type-specific distribution in adult rat kidney. Histochem. Cell Biol. 120:143-60.

Comelli, E., Amado, M., Head, S., and Paulson, J.C. (2002) Custom microarray for glycobiologists: considerations for glycosyltransferases gene expression profilin. K. Drickamer and A. Dell (eds.), In Glycogenomics: the Impact of Genomics and Informatics on Glycobiology, vol. 69. Portland Press Ltd, London, p. 135-42.

Collins, B.E., Blixt, O., Bovin, N. V., Danzer, C.P., Chui, D., Marth, J.D., Nitschke, L., and Paulson, J.C. (2002) Constitutively unmasked CD22 on B cells of ST6Gal I knockout mice: novel sialoside probe for murine CD22. Glycobiology 12:563-71.

Blixt, O., Allin, K., Pereira, L., Datta, A., and Paulson, J.C. (2002) Efficient chemoenzymatic synthesis of o-linked sialyl oligosaccharides. J. Amer. Chem. Soc. 124:5739-46.

Fazio, F., Bryan, M.C., Blixt, O., Paulson, J.C., and Wong, C.H. (2002) Synthesis of sugar arrays in microtiter plate. J. Amer. Chem. Soc. 124:14397-14402.

Dormitzer, P.R., Sun, Z. Y., Blixt, O., Paulson, J. C., Wagner, G., and Harrison, S.C. (2002) Specificity and affinity of sialic acid binding by the rhesus rotavirus VP8* core. J. Virol. 76:10512-10517.

Saito, S., Yamashita, S., Endoh, M., Yamato, T., Hoshi, S., Ohyama, C., Watanabe, R., Ito, A., Satoh, M., Wada, T., Paulson, J.C., Arai, Y., and Miyagi, T. (2002) Clinical significance of ST3Gal IV expression in human renal cell carcinoma. Oncol. Rep. 9:1251-5.

Lee, K. J., Mao, S., Sun, C., Gao, C., Blixt, O., Arrues, S., Hom, L.G., Kaufmann, G.F., Hoffman, T.Z., Coyle, A.R., Paulson, J.C., Felding-Habermann, B., and Janda, K. D. (2002) Phage-display selection of a human single-chain fv antibody highly specific for melanoma and breast cancer cells using a chemoenzymatically synthesized G(M3)-carbohydrate antigen. J. Amer. Chem. Soc. 124:12439-46.

Blixt, O., Brown, J., Schur, M. J., Wakarchuk, W., and Paulson, J. C. (2001) Efficient preparation of natural and synthetic galactosides with a recombinant beta-1,4-galactosyltransferase-/UDP-4'-gal epimerase fusion protein. J. Org. Chem. 66:2442-2448.

Datta, A., Chammas, R., and Paulson, J. (2001) Conserved cysteines in the sialyltransferase sialylmotifs form an essential disulfide bond. J. Biol. Chem. 276:15200-15207.

Alexander, J., del Guercio, M-F., Maewal, A., Qiao, L., Fikes, J., Chesnut, R.W., Paulson, J.C., Bundle, D.R., DeFrees, S. and Sette, A. (2000) Linear PADRE T helper epitope and carbohydrate B cell epitope conjugates induce specific high titer IgG antibody responses. J. Immunol. 164:1625-1633.

Paulson, J. C., Varki, A., and Esko, J. D. (1999) Glycobiology in biotechnology and medicine. Varki, A., Esko, J., Cummings, R., Freeze, H. H., Hart, G. W. & Marth, J., (eds.), In Essentials of Glycobiolgy, J. Cold Spring Harbor Laboratory Press, Plainview, NY, USA, pp. 625-634.

Hennet, T., Chui, D., Paulson, J. C., and Marth, J. D. (1998) Immune regulation by the ST6Gal sialyltransferase. Proc. Natl. Acad. Sci. USA 95:4504-9.

Talbott, G. A., Sharar, S. R., Paulson, J. C., Harlan, J. M., and Winn, R. K. (1998) Antibiotic therapy determines subcutaneous Escherichia coli abscess formation after CD18 inhibition in rabbits. J. Burn Care Rehabil. 19:284-91.

Datta, A. K., Sinha, A., and Paulson, J. C. (1998) Mutation of the sialyltransferase S-sialylmotif alters the kinetics of the donor and acceptor substrates. J. Biol. Chem. 273:9608-14.

Ito, T., Couceiro, J. N., Kelm, S., Baum, L. G., Krauss, S., Castrucci, M. R., Donatelli, I., Kida, H., Paulson, J. C., Webster, R. G., and Kawaoka, Y. (1998) Molecular basis for the generation in pigs of influenza A viruses with pandemic potential. J. Virol. 72:7367-73.

Tsuji, S., Datta, A. K., and Paulson, J. C. (1997) Systematic nomenclature for sialyltransferases. Glycobiology 6:5-14.

Datta, A. K. and Paulson, J. C. (1996) Sialylmotifs of sialyltransferases. Indian J. Biochem. Biophys. 34:157-65.

Sjoberg, E. R., Kitagawa, H., Glushka, J., van Halbeek, H., and Paulson, J. C. (1996) Molecular cloning of a developmentally regulated N-acetylgalactosamine a2,6-sialyltransferase specific for sialylated glycoconjugates. J. Biol. Chem. 271:450-9.

Wakefield, T. W., Strieter, R. M., Downing, L. J., Kadell, A. M., Wilke, C. A., Burdick, M. D., Wrobleski, S. K., Phillips, M. L., Paulson, J. C., Anderson, D. C., and Greenfield, L. J. (1996) P-selectin and TNF inhibition reduce venous thrombosis inflammation. J. Surg. Res. 64:26-31.

Tojo, S. J., Yokota, S., Koike, H., Schultz, J., Hamazume, Y., Misugi, E., Yamada, K., Hayashi, M., Paulson, J. C., and Morooka, S. (1996) Reduction of rat myocardial ischemia and reperfusion injury by sialyl Lewis x oligosaccharide and anti-rat P-selectin antibodies. Glycobiology 6:463-9.

Paulson, J. C. (1996) Leukocyte adhesion deficiency type II. Montreuit, J., Vliengenthart, J. F. G. & Schachter, H. (eds.), In Glycoproteins and Disease, Elsevier Science B.V., Netherlands, pp. 405-411.

Kitagawa, H., Mattei, M. G., and Paulson, J. C. (1996) Genomic organization and chromosomal mapping of the Galb1,3GalNAc/Galb1,4GlcNAc a2,3-sialyltransferase. J. Biol. Chem. 271:931-8.

Datta, A. K. and Paulson, J. C. (1995) The sialyltransferase ' sialylmotif ' participates in binding the donor substrate CMP-NeuAc. J. Biol. Chem. 270:1497-500.

Murohara, T., Margiotta, J., Phillips, L. M., Paulson, J. C., DeFrees, S., Zalipsky, S., Guo, L. S., and Lefer, A. M. (1995) Cardioprotection by liposome-conjugated sialyl Lewisx-oligosaccharide in myocardial ischaemia and reperfusion injury. Cardiovasc. Res. 30:965-74.

Williams, M. A., Kitagawa, H., Datta, A. K., Paulson, J. C., and Jamieson, J. C. (1995) Large-scale expression of recombinant sialyltransferases and comparison of their kinetic properties with native enzymes. Glycoconj. J. 12:755-61.

Etzioni, A., Phillips, L. M., Paulson, J. C., and Harlan, J. M. (1995) Leukocyte adhesion deficiency (LAD) II. Ciba Found. Symp. 189:51-8.

DeFrees, S. A., Kosch, W., Way, W., Paulson, J. C., Sabesan, S., Halcomb, R. L., Huang, D.-H., Ichikawa, Y., and Wong, C.-H. (1995) Ligand recognition by E-selectin: Synthesis, inhibitory activity, and conformational analysis of bivalent sialyl Lewisx analogs. J. Amer. Chem. Soc. 117:66-79.

Phillips, M. L., Schwartz, B. R., Etzioni, A., Bayer, R., Ochs, H. D., Paulson, J. C., and Harlan, J. M. (1995) Neutrophil adhesion in leukocyte adhesion deficiency syndrome type 2. J. Clin. Invest. 96:2898-906.

Leigh, M. W., Connor, R. J., Kelm, S., Baum, L. G., and Paulson, J. C. (1995) Receptor specificity of influenza virus influences severity of illness in ferrets. Vaccine 13:1468-73.

Jerome, S. N., Dore, M., Paulson, J. C., Smith, C. W., and Korthuis, R. J. (1994). P-selectin and ICAM-1-dependent adherence reactions: role in the genesis of postischemic no-reflow. Amer. J. Physiol. 266:H1316-21.

Gaudino, J. J. and Paulson, J. C. (1994) A novel and efficient synthesis of neolacto series gangliosides 3' -nLM1 and 6' -nLM1. J. Amer. Chem. Soc. 116:1149-1150.

Zimmerman, B. J., Paulson, J. C., Arrhenius, T. S., Gaeta, F. C., and Granger, D. N. (1994) Thrombin receptor peptide-mediated leukocyte rolling in rat mesenteric venules: roles of P-selectin and sialyl Lewis X. Amer. J. Physiol. 267:H1049-53.

Schuster, M., Wang, P., Paulson, J. C., and Wong, C.-H. (1994) Solid-phase chemical-enzymatic synthesis of glycopeptides and oligosaccharides. J. Amer. Chem. Soc. 116:1135-1136.

Zimmerman, B. J., Holt, J. W., Paulson, J. C., Anderson, D. C., Miyasaka, M., Tamatani, T., Todd, R. F., 3rd, Rusche, J. R., and Granger, D. N. (1994) Molecular determinants of lipid mediator-induced leukocyte adherence and emigration in rat mesenteric venules. Amer. J. Physiol. 266:H847-53.

Asako, H., Kurose, I., Wolf, R., DeFrees, S., Zheng, Z. L., Phillips, M. L., Paulson, J. C., and Granger, D. N. (1994). Role of H1 receptors and P-selectin in histamine-induced leukocyte rolling and adhesion in postcapillary venules. J. Clin. Invest. 93:1508-15.

Connor, R. J., Kawaoka, Y., Webster, R. G., and Paulson, J. C. (1994) Receptor specificity in human, avian, and equine H2 and H3 influenza virus isolates. Virology 205:17-23.

Kitagawa, H. and Paulson, J. C. (1994) Cloning of a novel a2,3-sialyltransferase that sialylates glycoprotein and glycolipid carbohydrate groups. J. Biol. Chem. 269:1394-401.

Forrest, M. and Paulson, J. C. (1994) Selectin family of adhesion molecules. N., G. D. & Schmid-Schönbein, G., (eds.), In Physiology and Pathophysiology of Leukocyte Adhesion, Oxford University Press, pp. 43-80.

Skurk, C., Buerke, M., Guo, J. P., Paulson, J., and Lefer, A. M. (1994) Sialyl Lewisx-containing oligosaccharide exerts beneficial effects in murine traumatic shock. Amer. J. Physiol. 267:H2124-31.

Kitagawa, H., and Paulson, J. C. (1994) Differential expression of five sialyltransferase genes in human tissues. J. Biol. Chem. 269:17872-8.

Kurose, I., Pothoulakis, C., LaMont, J. T., Anderson, D. C., Paulson, J. C., Miyasaka, M., Wolf, R., and Granger, D. N. (1994) Clostridium difficile toxin A-induced microvascular dysfunction. Role of histamine. J. Clin. Invest. 94:1919-26.

Kurose, I., Anderson, D. C., Miyasaka, M., Tamatani, T., Paulson, J. C., Todd, R. F., Rusche, J. R., and Granger, D. N. (1994) Molecular determinants of reperfusion-induced leukocyte adhesion and vascular protein leakage. Circ. Res. 74:336-43.

Unverzagt, C., Kelm, S., and Paulson, J. C. (1994) Chemical and enzymatic synthesis of multivalent sialoglycopeptides. Carbohydr. Res. 251:285-301.

Paulson, J. C. (1994) Selectins as therapeutic targets for inflammatory diseases. Strand, V. (ed.), In Proceedings: Early Decision in DMARD Development III. Arthritis Foundation, Atlanta, GA, (Biologic Agents in Autoimmune Disease Conference, 1993), pp. 52-54.

Winn, R. K., Paulson, J. C., and Harlan, J. M. (1994) A monoclonal antibody to P-selectin ameliorates injury associated with hemorrhagic shock in rabbits. Amer. J. Physiol. 267:H2391-7.

Seekamp, A., Till, G. O., Mulligan, M. S., Paulson, J. C., Anderson, D. C., Miyasaka, M., and Ward, P. A. (1994). Role of selectins in local and remote tissue injury following ischemia and reperfusion. Amer. J. Pathol. 144:592-8.

Sabesan, S., Paulson, J. C., and Weinstein, J. (1994) Separation of Galb1,4GlcNAc a-2,6- and Galb1,3(4)GlcNAc a2,3-sialyltransferases by affinity chromatography. Methods Enzymol. 247:237-43.

Kurose, I., Kubes, P., Wolf, R., Anderson, D. C., Paulson, J., Miyasaka, M., and Granger, D. N. (1993) Inhibition of nitric oxide production. Mechanisms of vascular albumin leakage. Circ. Res. 73:164-71.

Gillespie, W., Paulson, J. C., Kelm, S., Pang, M., and Baum, L. G. (1993) Regulation of a2,3-sialyltransferase expression correlates with conversion of peanut agglutinin PNA+ to PNA- phenotype in developing thymocytes. J. Biol. Chem. 268:3801-4.

Paulson, J. C. (1993) Carbohydrate ligands of leukocyte adhesion molecules and their therapeutic potential. Svennerholm, L., Ashbury, A. K., Reisfeld, R. A., Sandhoff, K., Suzuki, K., Tettamanti, G., & Toffano, G., (eds.), In Progress in Brian Research, Elsevier Science Publishers, pp. 179-184.

Ito, Y. and Paulson, J. C. (1993) Novel strategy for synthesis of ganglioside GM3 using an enzymatically produced sialoside glycosyl donor. J. Amer. Chem. Soc. 115:1603-1605.

Livingston, B. D. and Paulson, J. C. (1993) Polymerase chain reaction cloning of a developmentally regulated member of the sialyltransferase gene family. J. Biol. Chem. 268:11504-7.

Herrmann, G. F., Ichikawa, Y., Wandrey, C., Gaeta, F. C. A., Paulson, J. C., and Wong, C.-H. (1993) A new multi-enzyme sysem for a one-pot synthesis of sialyl oligosaccharides: Combined use of b-galactosidase and a(2,6)-sialyltransferase coupled with regeneration in situ of CMP-sialic acid. Tetrahedron Lett. 34:3091-3094.

Kitagawa, H., and Paulson, J. C. (1993) Cloning and expression of human Galb1,3(4)GlcNAc a2,3- sialyltransferase. Biochem. Biophys. Res. Commun. 194:375-82.

Ito, Y., and Paulson, J. C. (1993) Combined use of trans-sialidase and sialytransferase for enzymatic synthesis of aNeuAc2*3bGal-OR. J. Amer. Chem. Soc. 115:7862-7863.

von Andrian, U. H., Berger, E. M., Ramezani, L., Chambers, J. D., Ochs, H. D., Harlan, J. M., Paulson, J. C., Etzioni, A., and Arfors, K. E. (1993) In vivo behavior of neutrophils from two patients with distinct inherited leukocyte adhesion deficiency syndromes. J. Clin. Invest. 91:2893-7.

Winn, R. K., Liggitt, D., Vedder, N. B., Paulson, J. C., and Harlan, J. M. (1993) Anti-P-selectin monoclonal antibody attenuates reperfusion injury to the rabbit ear. J. Clin. Invest. 92:2042-7.

Aubin, Y., Ito, Y., Paulson, J. C., and Prestegard, J. H. (1993) Structure and dynamics of the sialic acid moiety of GM3-ganglioside at the surface of a magnetically oriented membrane. Biochemistry 32:13405-13.

Sharar, S. R., Sasaki, S. S., Flaherty, L. C., Paulson, J. C., Harlan, J. M., and Winn, R. K. (1993) P-selectin blockade does not impair leukocyte host defense against bacterial peritonitis and soft tissue infection in rabbits. J. Immunol. 151:4982-8.

Couceiro, J. N., Paulson, J. C., and Baum, L. G. (1993) Influenza virus strains selectively recognize sialyloligosaccharides on human respiratory epithelium; the role of the host cell in selection of hemagglutinin receptor specificity. Virus Res. 29:155-65.

Ito, Y., Gaudino, J. J., and Paulson, J. C. (1993) Synthesis of bioactive sialosides. Intl. Union Pure and App. Chem. 65:753-762.

Mulligan, M. S., Paulson, J. C., De Frees, S., Zheng, Z. L., Lowe, J. B., and Ward, P. A. (1993) Protective effects of oligosaccharides in P-selectin-dependent lung injury. Nature 364:149-51.

Mulligan, M.S., Lowe, J.B., Larsen, R.D., Paulson, J., Zheng, Z.L., DeFrees, S., Maemura, K., Fukuda, M., Ward, P.A. (1993) Protective effects of sialylated oligosaccharides in immune complex-induced acute lung injury. J. Exp. Med. 178:623-31.

Sabesan, S., Duus, J. O., Neira, S., Domaille, P., Kelm, S., Paulson, J. C., and Bock, K. (1992) Cluster Sialoside Inhibitors For Influenza Virus - Synthesis, Nmr, and Biological Studies. J. Amer. Chem. Soc. 114:8363-8375.

Paulson, J. C. (1992) Selectin/carbohydrate-mediated adhesion of leukocytes. Harlan, J. & Liu, D. (eds.), In Adhesion: Its Role in Inflammatory Disease. W. H. Freeman Publishing, New York, pp. 19-42.

Ichikawa, Y., Lin, Y.-C., Dumas, D. P., Shen, G.-J., Garcia-Junceda, E., Williams, M. A., Bayer, R., Ketcham, C., Walker, L. E., Paulson, J. C., and Wong, C.-H. (1992) Chemical-enzymatic synthesis and conformational analysis of sialyl Lewisx and derivatives. J. Amer. Chem. Soc. 114:9283-9298.

Svensson, E. C., Conley, P. B., and Paulson, J. C. (1992) Regulated expression of alpha 2,6-sialyltransferase by the liver-enriched transcription factors HNF-1, DBP, and LAP. J. Biol. Chem. 267:3466-72.

Kelm, S., Paulson, J. C., Rose, U., Brossmer, R., Schmid, W., Bandgar, B. P., Schreiner, E., Hartmann, M., and Zbiral, E. (1992) Use of sialic acid analogues to define functional groups involved in binding to the influenza virus hemagglutinin. Eur. J. Biochem. 205:147-53.

Wen, D. X., Svensson, E. C., and Paulson, J. C. (1992) Tissue-specific alternative splicing of the b-galactoside a2,6- sialyltransferase gene. J. Biol. Chem. 267:2512-8.

Herrler, G., Gross, H. J., Imhof, A., Brossmer, R., Milks, G., and Paulson, J. C. (1992) A synthetic sialic acid analogue is recognized by influenza C virus as a receptor determinant but is resistant to the receptor-destroying enzyme. J. Biol. Chem. 267:12501-5.

Wen, D. X., Livingston, B. D., Medzihradszky, K. F., Kelm, S., Burlingame, A. L., and Paulson, J. C. (1992) Primary structure of Gal b1,3(4)GlcNAc alpha 2,3-sialyltransferase determined by mass spectrometry sequence analysis and molecular cloning. Evidence for a protein motif in the sialyltransferase gene family. J. Biol. Chem. 267:21011-9.

Gillespie, W., Kelm, S., and Paulson, J. C. (1992) Cloning and expression of the Gal b1,3GalNAc a2,3 sialyltransferase. J. Biol. Chem. 267:21004-10.

Mulligan, M. S., Polley, M. J., Bayer, R. J., Nunn, M. F., Paulson, J. C., and Ward, P. A. (1992) Neutrophil-dependent acute lung injury. Requirement for P-selectin (GMP- 140). J. Clin. Invest. 90:1600-7.

Colley, K. J., Lee, E. U., and Paulson, J. C. (1992) The signal anchor and stem regions of the b-galactoside a2,6- sialyltransferase may each act to localize the enzyme to the Golgi apparatus. J. Biol. Chem. 267:7784-93.

Etzioni, A., Frydman, M., Pollack, S., Avidor, I., Phillips, M. L., Paulson, J. C., and Gershoni-Baruch, R. (1992) Brief report: recurrent severe infections caused by a novel leukocyte adhesion deficiency. N. Engl. J. Med. 327:1789-92.

Pozsgay, V., Brisson, J.-R., Jennings, H. J., Allen, S., and Paulson, J. C. (1991) Combined chemical and enzymatic synthesis of a pentasaccharide repeating unit of he capsular polysaccharide of type III group B streptococcus and one- and two-dimensional NMR spectroscopic studies. J. Org. Chem. 56:3377-3385.

Pozsgay, V., Gaudino, J., Paulson, J. C., and Jennings, H. J. (1991). Chem-enzymatic synthesis of a branching decasaccharide fragment of the capsular polysacharide of type III group B streptococcus. Bioorg. & Med. Chem. Lett. 1:391-394.

Polley, M. J., Phillips, M. L., Wayner, E., Nudelman, E., Singhal, A. K., Hakomori, S., and Paulson, J. C. (1991) CD62 and endothelial cell-leukocyte adhesion molecule 1 (ELAM-1) recognize the same carbohydrate ligand, sialyl-Lewis x. Proc. Natl. Acad. Sci. USA 88:6224-8.

Kodama, H., Baum, L. G., and Paulson, J. C. (1991) Synthesis of linkage-specific sialoside substrates for colorimetric assay of neuraminidases. Carbohydr. Res. 218:111-9.

Baum, L. G., and Paulson, J. C. (1991) The N2 neuraminidase of human influenza virus has acquired a substrate specificity complementary to the hemagglutinin receptor specificity. Virology 180:10-5.

Sabesan, S., Bock, K., and Paulson, J. C. (1991). Conformational analysis of sialyloligosaccharides. Carbohydr. Res. 218:27-54.

Nishi, T., Weinstein, J., Gillespie, W. M., and Paulson, J. C. (1991) Complete primary structure of porcine tenascin. Detection of tenascin transcripts in adult submaxillary glands. Eur. J. Biochem. 202:643-8.

Svensson, E. C., Lee, E. U., Livingston, B., Wen, X., Weinstein, J., and Paulson, J. C. (1991) Regulation of terminal glycosylation. Conradt, H. S., (ed.), In Protein Glycosylation: Cellular, Biotechnological and Analytical Aspects Vol. 15, VCH Publishing Weinheim, New York, Cambridge, pp. 207-208.

Crocker, P. R., Kelm, S., Dubois, C., Martin, B., McWilliam, A. S., Shotton, D. M., Paulson, J. C., and Gordon, S. (1991) Purification and properties of sialoadhesin, a sialic acid-binding receptor of murine tissue macrophages. Embo. J. 10:1661-9.

Bevilacqua, M.; Butcher, E.; Furie, B.; Furie, B.; Gallatin, M.; Gimbrone, M.; Harlan, J.; Kishimoto, K.; Lasky, L.; McEver, R.; Paulson, J.; Rosen, S.; Seed, B.; Siegelman, M.; Springer, T.; Stoolman, L.; Tedder, T.; Varki, A.; Wagner, D.; Weissman, I.; Zimmerman, G. (1991) Selectins: a family of adhesion receptors. (Letter) Cell 67: 233.

Sabesan, S., Duus, J., Domaille, P., Kelm, S., and Paulson, J. C. (1991) Synthesis of cluster sialoside inhibitors for influenza virus. J. Amer. Chem. Soc. 113:5865-66.

Baum, L. G. and Paulson, J. C. (1990) Sialyloligosaccharides of the respiratory epithelium in the selection of human influenza virus receptor specificity. Acta. Histochem. Suppl. 40:35-8.

Phillips, M. L., Nudelman, E., Gaeta, F. C., Perez, M., Singhal, A. K., Hakomori, S., and Paulson, J. C. (1990) ELAM-1 mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex. Science 250:1130-2.

Herrler, G., Gross, H. J., Milks, G., Paulson, J. C., Klenk, H. D., and Brossmer, R. (1990) Use of a sialic acid analogue to analyze the importance of the receptor- destroying enzyme for the interaction of influenza C virus with cells. Acta. Histochem. Suppl. 40:39-41.

Unverzgat, C., Kunz, H., and Paulson, J. C. (1990) High efficiency synthesis of sialyloligosaccharides and sialoglycopeptides. J. Amer. Chem. Soc. 112:9308-9309.

Svensson, E. C., Soreghan, B., and Paulson, J. C. (1990) Organization of the beta-galactoside alpha 2,6-sialyltransferase gene. Evidence for the transcriptional regulation of terminal glycosylation. J. Biol. Chem. 265:20863-8.

Livingston, B. D., De Robertis, E. M., and Paulson, J. C. (1990) Expression of beta-galactoside alpha 2,6 sialyltransferase blocks synthesis of polysialic acid in Xenopus embryos. Glycobiology 1:39-44.

Colley, K. J., Lee, E. U., Adler, B., Browne, J. K., and Paulson, J. C. (1989) Conversion of a Golgi apparatus sialyltransferase to a secretory protein by replacement of the NH2-terminal signal anchor with a signal peptide. J. Biol. Chem. 264:17619-22.

Paulson, J. C., Weinstein, J., and Schauer, A. (1989) Tissue-specific expression of sialyltransferases. J. Biol. Chem. 264:10931-4.

Paulson, J. C. (1989) Glycoproteins: what are the sugar chains for? Trends Biochem. Science 14:272-6.

Paulson, J. C. and Colley, K. J. (1989) Glycosyltransferases. Structure, localization, and control of cell type- specific glycosylation. J. Biol. Chem. 264:17615-8.

Pritchett, T. J. and Paulson, J. C. (1989) Basis for the potent inhibition of influenza virus infection by equine and guinea pig a2-macroglobulin. J. Biol. Chem. 264:9850-8.

Gross, H. J., Rose, U., Krause, J. M., Paulson, J. C., Schmid, K., Feeney, R. E., and Brossmer, R. (1989) Transfer of synthetic sialic acid analogues to N- and O-linked glycoprotein glycans using four different mammalian sialyltransferases. Biochemistry 28:7386-92.

Hanaoka, K., Pritchett, T. J., Takasaki, S., Kochibe, N., Sabesan, S., Paulson, J. C., and Kobata, A. (1989) 4-O-acetyl-N-acetylneuraminic acid in the N-linked carbohydrate structures of equine and guinea pig a2-macroglobulins, potent inhibitors of influenza virus infection. J. Biol. Chem. 264:9842-9.

Lee, E. U., Roth, J., and Paulson, J. C. (1989) Alteration of terminal glycosylation sequences on N-linked oligosaccharides of Chinese hamster ovary cells by expression of b-galactoside a2,6-sialyltransferase. J. Biol. Chem. 264:13848-55.

Ravindranaths, M. H., Paulson, J. C., and Irie, R. F. (1988) Human melanoma antigen O-acetylated ganglioside GD3 is recognized by Cancer antennarius lectin. J. Biol. Chem. 263:2079-86.

Weis, W., Brown, J. H., Cusack, S., Paulson, J. C., Skehel, J. J., and Wiley, D. C. (1988) Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid. Nature 333:426-31.

Taatjes, D. J., Roth, J., Weinstein, J., and Paulson, J. C. (1988) Post-Golgi apparatus localization and regional expression of rat intestinal sialyltransferase detected by immunoelectron microscopy with polypeptide epitope-purified antibody. J. Biol. Chem. 263:6302-9.

Ravindranath, M. H.,and Paulson, J. C. (1987) O-acetylsialic acid-specific lectin from the crab Cancer anntenarius. Methods Enzymol. 138:520-7.

Pritchett, T. J., Brossmer, R., Rose, U., and Paulson, J. C. (1987) Recognition of monovalent sialosides by influenza virus H3 hemagglutinin. Virology 160:502-6.

Paulson, J. C., and Rogers, G. N. (1987) Resialylated erythrocytes for assessment of the specificity of sialyloligosaccharide binding proteins. Methods Enzymol. 138:162-8.

Paulson, J. C., Weinstein, J., Ujita, E. L., Riggs, K. J., and Lai, P. H. (1987) The membrane-binding domain of a rat liver Golgi sialyltransferase. Biochem. Soc. Trans. 15:618-20.

Daniels, P. S., Jeffries, S., Yates, P., Schild, G. C., Rogers, G. N., Paulson, J. C., Wharton, S. A., Douglas, A. R., Skehel, J. J., and Wiley, D. C. (1987) The receptor-binding and membrane-fusion properties of influenza virus variants selected using anti-haemagglutinin monoclonal antibodies. Embo. J. 6:1459-65.

Weinstein, J., Lee, E. U., McEntee, K., Lai, P. H., and Paulson, J. C. (1987) Primary structure of b-galactoside a2,6-sialyltransferase. Conversion of membrane-bound enzyme to soluble forms by cleavage of the NH2-terminal signal anchor. J. Biol. Chem. 262:17735-43.

Gross, H. J., Bunsch, A., Paulson, J. C., and Brossmer, R. (1987) Activation and transfer of novel synthetic 9-substituted sialic acids. Eur. J. Biochem. 168:595-602.

Taatjes, D. J., Roth, J., Weinstein, J., Paulson, J. C., Shaper, N. L., and Shaper, J. H. (1987) Codistribution of galactosyl- and sialyltransferase: reorganization of trans Golgi apparatus elements in hepatocytes in intact liver and cell culture. Eur. J. Cell. Biol. 44:187-94.

Rogers, G. N., Herrler, G., Paulson, J. C., and Klenk, H. D. (1986) Influenza C virus uses 9-O-acetyl-N-acetylneuraminic acid as a high affinity receptor determinant for attachment to cells. J. Biol. Chem. 261:5947-51.

Kelm, S., Shukla, A. K., Paulson, J. C., and Schauer, R. (1986) Reconstitution of the masking effect of sialic acid groups on sialidase- treated erythrocytes by the action of sialyltransferases. Carbohydr. Res. 149:59-64.

Paulson, J. C., Rogers, G. N., Murayama, J.-I., Sze, G., and Martin, E. (1986) Biological impliations of influenza virus receptor specificity. Crowell, R. L. & Lonberg-Holm, K. (eds.), In Virus Attachment and Entry into Cells, American Society Microbiology, Washington D. C., pp. 144-151.

Sabesan, S. and Paulson, J. C. (1986) Combined chemical and enzymatic synthesis of sialyloligosacharides and characterization by 500-MHz 1H and 13C NMR spectorscopy. J. Amer. Soc. Chem. 108:2068-2080.

Roth, J., Taatjes, D. J., Weinstein, J., Paulson, J. C., Greenwell, P., and Watkins, W. M. (1986) Differential subcompartmentation of terminal glycosylation in the Golgi apparatus of intestinal absorptive and goblet cells. J. Biol. Chem. 261:14307-12.

Roth, J., Taatjes, D. J., Lucocq, J. M., Weinstein, J., and Paulson, J. C. (1985) Demonstration of an extensive trans-tubular network continuous with the Golgi apparatus stack that may function in glycosylation. Cell 43:287-95.

Rogers, G. N., Daniels, R. S., Skehel, J. J., Wiley, D. C., Wang, X. F., Higa, H. H., and Paulson, J. C. (1985) Host-mediated selection of influenza virus receptor variants. Sialic acid-a2,6Gal-specific clones of A/duck/Ukraine/1/63 revert to sialic acid-a2,3Gal-specific wild type in ovo. J. Biol. Chem. 260:7362-7.

Ravindranath, M. H., Higa, H. H., Cooper, E. L., and Paulson, J. C. (1985) Purification and characterization of an O-acetylsialic acid-specific lectin from a marine crab Cancer antennarius. J. Biol. Chem. 260:8850-6.

Carroll, S. M. and Paulson, J. C. (1985) Differential infection of receptor-modified host cells by receptor- specific influenza viruses. Virus. Res. 3:165-79.

Paulson, J. C. (1985) Interactions of animal viruses with cell surface receptors. Conn, M. (ed.), In The Receptors Volume 2, Academic Press, Orlando, pp. 131-219. [ISBN: 0121852024]

Higa, H. H. and Paulson, J. C. (1985) Sialylation of glycoprotein oligosaccharides with N-acetyl-, N-glycolyl-, and N-O-diacetylneuraminic acids. J. Biol. Chem. 260:8838-49.

Higa, H. H. and Paulson, J. C. (1985) Purification of the N-acetylgalactosaminide a2,6 sialytransferase from bovine submaxillary glands (Appendix). J. Biol. Chem. 260:8848-8849.

Higa, H. H., Rogers, G. N., and Paulson, J. C. (1985) Influenza virus hemagglutinins differentiate between receptor determinants bearing N-acetyl-, N-glycollyl-, and N,O- diacetylneuraminic acids. Virology 144:279-82.

Crowell, R. L., Fields, B., Minor, P., Norrby, E. C. J., Paulson, J. C., Skehel, J. J., Schild, G. C., Assaad, F., and Bektimarov, T. (1985) Relevance of studies of cellular receptors to the prevention and control of viral disease: Memorandum from a WHO meeting. Bull. WHO 63:1009-1012.

Sabesan, S., Bock, K., and Paulson, J. C. (1985) Synthesis of sialyloligosaccharides and the determination of their conformational properties based on HSEA calculations and NMR spectroscopy. Davidson, E. A., Williams, J. C. & DiFerrante, N. M. (eds.), In Glycoconjugates: Proceedings of the VIII International Symposium, Praeger Publisher, New York, pp. 473-474.

Rogers, G. N., Wang, X.-F., Pritchett, T. J., Haer, L. F., and Paulson, J. C. (1984) Selection of receptor variants from human and avian influenza isolates with the H3 hemagglutinin. Compans, R. W. & Bishop, D. H. L. (eds.), In Segmented Negative Stranded Viruses, Academic Press, San Diego, pp. 239-246.

Paulson, J. C., Rogers, G. N., Carroll, S. M., Higa, H. H., Pritchett, T., G., M., and Sabesan, S. (1984) Selection of influenza variants based on sialyloligosaccharides receptor specificity. Pure App. Chem. 56:797-805.

Paulson, J. C., Weinstein, J., and de Souza-e-Silva, U. (1984). Biosynthesis of a disialylated sequence in N-linked oligosaccharides: identification of an N-acetylglucosaminide a2,6 sialyltransferase in Golgi apparatus from rat liver. Eur. J. Biochem. 140:523-30.

Daniels, R. S., Douglas, A. R., Skehel, J. J., Wiley, D. C., Naeve, C. W., Webster, R. G., Rogers, G. N., and Paulson, J. C. (1984) Antigenic analyses of influenza virus haemagglutinins with different receptor-binding specificities. Virology 138:174-7.

Tai, T., Cahan, L. D., Paulson, J. C., Saxton, R. E., and Irie, R. F. (1984) Human monoclonal antibody against ganglioside GD2: use in development of enzyme-linked immunosorbent assay for the monitoring of anti-GD2 in cancer patients. J. Natl. Cancer Inst. 73:627-33.

Skehel, J. J., Daniels, R. S., Douglas, A. R., Knossow, M., Paulson, J. C., Rogers, G. N., Waterfield, M. D., Wilson, I. A., and Wiley, D. C. (1984) Studies on the structure and activities of influenza virus hemagglutinin. Kohn, A. & Fuchs, P. (eds.), In Mechanisms of Vial Pathogenesis, M. Nijhoff Publishing, Boston, pp. 217-225.

Loomes, L. M., Uemura, K., Childs, R. A., Paulson, J. C., Rogers, G. N., Scudder, P. R., Michalski, J. C., Hounsell, E. F., Taylor-Robinson, D., and Feizi, T. (1984) Erythrocyte receptors for Mycoplasma pneumoniae are sialylated oligosaccharides of Ii antigen type. Nature 307:560-3.

Rogers, G. N. and Paulson, J. C. (1983) Receptor determinants of human and animal influenza virus isolates: differences in receptor specificity of the H3 hemagglutinin based on species of origin. Virology 127:361-73.

Rogers, G. N., Paulson, J. C., Daniels, R. S., Skehel, J. J., Wilson, I. A., and Wiley, D. C. (1983) Single amino acid substitutions in influenza haemagglutinin change receptor binding specificity. Nature 304:76-8.

Rogers, G. N., Pritchett, T. J., Lane, J. L., and Paulson, J. C. (1983) Differential sensitivity of human, avian, and equine influenza A viruses to a glycoprotein inhibitor of infection: selection of receptor specific variants. Virology 131:394-408.

Paulson, J. C., Rogers, G. N., Pritchett, T., Haber, L., and Carroll, S. M. (1983) Selection of receptor specific variants of influenza virus. In Glycoconjugates: Proceedings of the VIIth International Symposium (Chester, M. A., Heinegard, D., Lundblad, A. & Svensson, S., eds.), pp. 647-648. Rahms Publisher, Lund.

Cahan, L. D., Singh, R., and Paulson, J. C. (1983) Sialyloligosaccharide receptors of binding variants of polyoma virus. Virology 130:281-9.

Tai, T., Paulson, J. C., Cahan, L. D., and Irie, R. F. (1983) Human tumor-associated antigen: Gangliosides GM2 and GD2. Chester, M. A., Heinegard, D., Lundblad, A. & Svensson, S. (eds.), In Glycoconjugates: Proceedings of the VIIth International Symposium, Rahms Publisher, Lund, pp. 847-848.

Tai, T., Paulson, J. C., Cahan, L. D.,and Irie, R. F. (1983) Ganglioside GM2 as a human tumor antigen (OFA-I-1). Proc. Natl. Acad. Sci. USA 80:5392-6.

Corfield, A. P., Higa, H., Paulson, J. C., and Schauer, R. (1983) The specificity of viral and bacterial sialidases for a(2-3) and a(2-6) linked sialic acids in glycoproteins. Biochim. Biophys. Acta. 744:121-6.

Carroll, S. M. and Paulson, J. C. (1982) Complete metal ion requirement of influenza virus N1 neuraminidases. Brief report. Arch. Virol. 71:273-7.

Paulson, J. C., Weinstein, J., and de Souza-e-Silva, U. (1982) Identification of a Gal b1,3GlcNAc a2,3 sialyltransferase in rat liver. J. Biol. Chem. 257:4034-7.

Paulson, J. C., Weinstein, J., Dorland, L., van Halbeek, H., and Vliegenthart, J. F. (1982) Newcastle disease virus contains a linkage-specific glycoprotein sialidase. Application to the localization of sialic acid residues in N- linked oligosaccharides of a1-acid glycoprotein. J. Biol. Chem. 257:12734-8.

Berger, E. G., Buddecke, E., Kamerling, J. P., Kobata, A., Paulson, J. C., and Vliegenthart, J. F. (1982) Structure, biosynthesis and functions of glycoprotein glycans. Experientia 38:1129-62.

Weinstein, J., de Souza-e-Silva, U., and Paulson, J. C. (1982) Purification of a Gal b1,4GlcNAc a2,6 sialyltransferase and a Gal b1,3(4)GlcNAc a2,3 sialyltransferase to homogeneity from rat liver. J. Biol. Chem. 257:13835-44.

Weinstein, J., de Souza-e-Silva, U., and Paulson, J. C. (1982) Sialylation of glycoprotein oligosaccharides N-linked to asparagine. Enzymatic characterization of a Gal b1,(4)GlcNAc a2,3 sialyltransferase and a Galb1,4GlcNAc a2,6 sialyltransferase from rat liver. J. Biol. Chem. 257:13845-53.

Cahan, L. D., Irie, R. F., Singh, R., Cassidenti, A., and Paulson, J. C. (1982) Identification of a human neuroectodermal tumor antigen (OFA-I-2) as ganglioside GD2. Proc. Natl. Acad. Sci. USA 79:7629-33.

Sadler, J. E., Beyer, T. A., Oppenheimer, C. L., Paulson, J. C., Prieels, J. P., Rearick, J. I., and Hill, R. L. (1982) Purification of mammalian glycosyltransferases. Methods Enzymol. 83:458-514.

Beyer, T. A., Sadler, J. E., Rearick, J. I., Paulson, J. C., and Hill, R. L. (1981) Glycosyltransferases and their use in assessing oligosaccharide structure and structure-function relationships. Adv. Enzymol. Relat. Areas. Mol. Biol. 52: 23-175.

Carroll, S. M., Higa, H. H., Cahan, L. D., and Paulson, J. C. (1981) Different sialyloligosaccharide receptor determinants of antigenically related influenza virus hemagglutinins. Nayak, D. & Fox, C. F. (eds.), In Genetic Variation in Influenza Viruses, Academic Press, New York, pp. 415-421.

Carroll, S. M., Higa, H. H., and Paulson, J. C. (1981) Different cell-surface receptor determinants of antigenically similar influenza virus hemagglutinins. J. Biol. Chem. 256:8357-63.

Markwell, M. A. K., Kruse, C. A., Paulson, J. C., and Svennerholm, L. (1981) Virus-host cell interaction during the adsorption-penetration phaase of paramyxovirus infection. Bishop, D. H. L. & Compans, R. W. (eds.), In The Replication of Negative Strand Viruses, Elsevier, New York, pp. 503-507.

Markwell, M. A., Svennerholm, L., and Paulson, J. C. (1981) Specific gangliosides function as host cell receptors for Sendai virus. Proc. Natl. Acad. Sci. USA 78:5406-10.

Fried, H., Cahan, L. D., and Paulson, J. C. (1981) Polyoma virus recognizes specific sialyligosaccharide receptors on host cells. Virology 109:188-92.

Hill, R. L., Pizzo, S. V., Imber, M., Lehrman, M., Prieels, J. P., Glasgow, L. R., Guthrow, C. E., and Paulson, J. C. (1980) Receptors on hepatocytes that bind ligands containing fucosyl a1,3 N-acetylgluco-samine linkages. Desnick, R. (ed.), In Enzyme Therapy in Gentic Disease: 2, Alan R. Liss, Inc., New York, pp. 85-91.

Hill, R. L., Beyer, T. A., Paulson, J. C., Prieels, J. P., Rearick, J. I., and Sadler, J. E. (1980) Glycosyltransferases in oligosaccharide biosynthesis and their use in structure-function analysis of glycoproteins. Anachenko, S. N. (ed.), In Frontiers of Bioorganic Chemistry and Molecular Biology, Pergamon Press, New York, pp. 63-71.

Markwell, M. A. and Paulson, J. C. (1980) Sendai virus utilizes specific sialyloligosaccharides as host cell receptor determinants. Proc. Natl. Acad. Sci. USA 77:5693-7.

Cahan, L. D. and Paulson, J. C. (1980) Polyoma virus adsorbs to specific sialyloligosaccharide receptors on erythrocytes. Virology 103:505-9.

Rearick, J. I., Sadler, J. E., Paulson, J. C., and Hill, R. L. (1979) Enzymatic characterization of bD-galactoside a2,3 sialyltransferase from porcine submaxillary gland. J. Biol. Chem. 254:4444-51.

Beyer, T., Rearick, J. I., Paulson, J. C., Prieels, J. P., Sadler, J. E., and Hill, R. L. (1979) Biosynthesis of mammalian glycoproteins. Glycosylation pathways in the synthesis of the nonreducing terminal sequences. J. Biol. Chem. 254:12531-4.

Paulson, J. C., Markwell, M. A. K., Cahan, L., Higa, H. H., Marshall, L., and Weinstein, J. (1979) The interaction of myxoviruses with sialyloligosaccharide receptors. Schauer, R., Boer, P., Buddecke, E., Kramer, M. F., Vliegenthart, J. F. G. & Wiegandt, H. (eds.),In Glycoconjugates Research, George Thieme Publisher, Stutgart, pp. 680-681.

Paulson, J. C., Glasgow, L. R., Beyer, T. A., Lowman, C., Holroyde, M., and Hill, R. L. (1979) Use of glycosyltransferases and glycosidases in structure analysis of oligosaccharides. Gregory, J. D. & Jeanloz, R. W. (eds.), In Glycoconjugate Research, Academic Press, New York, pp. 247-250.

Paulson, J. C., Sadler, J. E., and Hill, R. L. (1979) Restoration of specific myxovirus receptors to asialoerythrocytes by incorporation of sialic acid with pure sialyltransferases. J. Biol. Chem. 254:2120-4.

Sodetz, J. M., Paulson, J. C., and McKee, P. A. (1979) Carbohydrate composition and identification of blood group A, B, and H oligosaccharide structures on human Factor VIII/von Willebrand factor. J. Biol. Chem. 254:10754-60.

Sadler, J. E., Rearick, J. I., Paulson, J. C., and Hill, R. L. (1979) Purification of two sialytransferase activities from porcine submaxillary glands. Gregory, J. D. & Jeanloz, R. W. (eds.), In Glycoconjugate Research, Academic Press, New York, pp. 763-766.

Sadler, J. E., Rearick, J. I., Paulson, J. C., and Hill, R. L. (1979) Purification to homogeneity of a b-galactoside a2,3 sialyltransferase and partial purification of an a-N- acetylgalactosaminide a2,6 sialyltransferase from porcine submaxillary glands. J. Biol. Chem. 254:4434-42.

Sadler, J. E., Paulson, J. C., and Hill, R. L. (1979) The role of sialic acid in the expression of human MN blood group antigens. J. Biol. Chem. 254:2112-9.

Prieels, J. P., Pizzo, S. V., Glasgow, L. R., Paulson, J. C., and Hill, R. L. (1978) Hepatic receptor that specifically binds oligosaccharides containing fucosyl a1,3 N-acetylglucosamine linkages. Proc. Natl. Acad. Sci. USA 75:2215-9.

Paulson, J. C., Prieels, J. P., Glasgow, L. R., and Hill, R. L. (1978) Sialyl- and fucosyltransferases in the biosynthesis of asparaginyl- linked oligosaccharides in glycoproteins. Mutually exclusive glycosylation by b-galactoside a2,6 sialyltransferase and N-acetylglucosaminide a1,3 fucosyltransferase. J. Biol. Chem. 253:5617-24.

Van Eldik, L. J., Paulson, J. C., Green, R. W., and Smith, R. E. (1978) The influence of carbohydrate on the antigenicity of the envelope glycoprotein of avian myeloblastosis virus and B77 avian sarcoma virus. Virology 86:193-204.

Sodetz, J. M., Paulson, J. C., Pizzo, S. V., andd McKee, P. A. (1978) Carbohydrate on human factor VIII/von Willebrand factor. Impairment of function by removal of specific galactose residues. J. Biol. Chem. 253:7202-6.

Hill, R. H., Paulson, J. C., Sadler, J. E., Rearick, J. I., Beyer, T. A., and Prieels, J. P. (1977) Isolation and characterization of glycosyltransferases. Uppsala J. Med. 82:75.

Paulson, J. C., Beranek, W. E., and Hill, R. L. (1977) Purification of a sialyltransferase from bovine colostrum by affinity chromatography on CDP-agarose. J. Biol. Chem. 252:2356-62.

Paulson, J. C., Rearick, J. I., and Hill, R. L. (1977) Enzymatic properties of b-D-galactoside a2,6 sialytransferase from bovine colostrum. J. Biol. Chem. 252:2363-71.

Paulson, J. C., Hill, R. L., Tanabe, T., and Ashwell, G. (1977) Reactivation of asialo-rabbit liver binding protein by resialylation with b-D-galactoside a2,6 sialyltransferase. J. Biol. Chem. 252:8624-8.

McClure, W. O. and Paulson, J. C. (1977). The interaction of colchicine and some related alkaloids with rat brain tubulin. Mol. Pharmacol. 13:560-75.

Glasgow, L. R., Paulson, J. C., and Hill, R. L. (1977) Systematic purification of five glycosidases from Streptococcus (Diplococcus) pneumoniae. J. Biol. Chem. 252:8615-23.

Paulson, J. C. and McClure, W. O. (1975) Inhibition of axoplasmic transport by colchicine, podophyllotoxin, and vinblastine: an effect on microtubules. Ann. NY Acad. Sci. 253:517-27.

Paulson, J. C. and McClure, W. O. (1975) Microtubules and axoplasmic transport. Inhibition of transport by podophyllotoxin: an interaction with microtubule protein. J. Cell. Biol. 67:461-7.

Paulson, J. C. and McClure, W. O. (1974) Microtubules and axoplasmic transport. Brain. Res. 73:333-7.

Paulson, J. C. and McClure, W. O. (1974) The lack of correlation between hallucinogenesis and inhibition of axoplasmic transport. Mol. Pharmacol. 10:419-24.

Paulson, J. C. and McClure, W. O. (1973) Inhibition of axoplasmic transport by mescaline and other trimethoxyphenylalkylamines. Mol. Pharmacol. 9:41-50.

Department of Chemical Physiology and Department of Molecular Biology, 10550 N. Torrey Pines Rd., MEML71, La Jolla, CA 92037