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| Ramya Thirumalai Nallan Chakravarthy, Ph.D.
The Scripps Research Institute 10550 N.Torrey Pines Road, MEM-L71 La Jolla , CA 92037 Tel. 00-1-858-784-9638 Fax 00-1-858-784-9690 ramya@scripps.edu |
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EDUCATION October 2006 Ph.D. in Molecular Biology, Indian Institute of Science, Bangalore,India 2000 M.Sc. in Biotechnology, University of Pune, Pune, India 1998 B.Sc. in Chemistry, Botany, Zoology, St. Francis' College for Women, Begumpet, (an autonomous college of Osmania University) Hyderabad,India RESEARCH EXPERIENCES 11/2006 - Present Postdoctoral Fellow, The Scripps Research Institute, La Jolla, CA (USA). Advisor: Prof. James C. Paulson 08/2000 - 2006 Graduate Student, Molecular Biophysics Unit, Indian Institute of Science, Bangalore (India). Supervisor: Prof. A. Surolia. 06/1999 - 2000 Researcher, Department of Biotechnology, University of Pune, Pune (India). Supervisor: Prof. V. Sitaramam. HONORS AND AWARDS 2005 Travel grant from Council of Scientific and Industrial Research (CSIR), Government of India, and Department of Science and Technology, Government of India 2002 Senior Research Fellowship, Council of Scientific and Industrial Research (CSIR), Government of India 2000-2002 Junior Research Fellowship, Council of Scientific and Industrial Research (CSIR), Government of India 2000 Qualified GATE-2000 Life Sciences examination with a percentile of 99.49 (All India Rank 8) 1998-2000 Scholarship, Department of Biotechnology (DBT), Government of India 1998-2000 Gold Medal for M.Sc. Biotechnology 1995-1998 P. Gandhian medal for Best All Rounder in B.Sc. 1995-1998 Regina Margaritha Prize for English in B.Sc. 1995-1998 Department of Chemistry Gold Medal for Chemistry in B.Sc. 1995-1998 Helen William Gold Medal for Zoology in B.Sc. 1995-1998 Pramila Rao Gold Medal for Botany in B.Sc. 1995-1998 Krishna Kakkar Memorial Gold Medal for B.Sc. PUBLICATIONS Ramya, T. N., Surolia, N. & Surolia, A. (2007). 15-deoxyspergualin inhibits eukaryotic protein synthesis through eIF2alpha phosphorylation. Biochem J 401, 411-20. Ramya, T. N., Mishra, S., Karmodiya, K., Surolia, N. & Surolia, A. (2007). Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum. Antimicrob Agents Chemother 51, 307-16. Ramya, T. N., Karmodiya, K., Surolia, A. & Surolia, N. (2007). 15-Deoxyspergualin Primarily Targets the Trafficking of Apicoplast Proteins in Plasmodium falciparum. J Biol Chem 282, 6388-97. Ramya, T. N., Surolia, N. & Surolia, A. (2006). 15-Deoxyspergualin modulates Plasmodium falciparum heat shock protein function. Biochem Biophys Res Commun 348, 585-92. Ramya, T. N., Surolia, N. & Surolia, A. (2006). Polyamine synthesis and salvage pathways in the malaria parasite Plasmodium falciparum. Biochem Biophys Res Commun 348, 579-84. Mitra, N., Sinha, S., Ramya, T. N. & Surolia, A. (2006). N-linked oligosaccharides as outfitters for glycoprotein folding, form and function. Trends Biochem Sci 31, 156-63. Chhibber, M., Kumar, G., Parasuraman, P., Ramya, T. N., Surolia, N. & Surolia, A. (2006). Novel diphenyl ethers: design, docking studies, synthesis and inhibition of enoyl ACP reductase of Plasmodium falciparum and Escherichia coli. Bioorg Med Chem 14, 8086-98. Ramya, T. N., Surolia, N. & Surolia, A. (2005). Is the fatty acid synthesis pathway a good target for anti-malarial therapy? IUBMB Life 57, 371-3. Kesavulu, M. M., Prakasha Gowda, A. S., Ramya, T. N., Surolia, N. & Suguna, K. (2005). Plasmepsin inhibitors: design, synthesis, inhibitory studies and crystal structure analysis. J Pept Res 66, 211-9. Surolia, A., Ramya, T. N., Ramya, V. & Surolia, N. (2004). 'FAS't inhibition of malaria. Biochem J 383, 401-12. Ramya, T. N. & Surolia, A. (2004). A Report on the XVII International Symposium on Glycoconjugates. Trends Glycosci Glycotech 16, 373-377. Kundhavai Natchiar, S., Arockia Jeyaprakash, A., Ramya, T. N., Thomas, C. J., Suguna, K., Surolia, A. & Vijayan, M. (2004). Structural plasticity of peanut lectin: an X-ray analysis involving variation in pH, ligand binding and crystal structure. Acta Crystallogr D Biol Crystallogr 60, 211-9. Sharma, S. K., Kapoor, M., Ramya, T. N., Kumar, S., Kumar, G., Modak, R., Sharma, S., Surolia, N. & Surolia, A. (2003). Identification, characterization, and inhibition of Plasmodium falciparum beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ). J Biol Chem 278, 45661-71. Sharma, S., Ramya, T. N., Surolia, A. & Surolia, N. (2003). Triclosan as a systemic antibacterial agent in a mouse model of acute bacterial challenge. Antimicrob Agents Chemother 47, 3859-66. Ramya, T. N., Surolia, N. & Surolia, A. (2002). Survival Strategies of the malarial parasite Plasmodium falciparum. . Current Science 83. Mitra, N., Srinivas, V. R., Ramya, T. N., Ahmad, N., Reddy, G. B. & Surolia, A. (2002). Conformational stability of legume lectins reflect their different modes of quaternary association: solvent denaturation studies on concanavalin A and winged bean acidic agglutinin. Biochemistry 41, 9256-63. |
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