Paulson Laboratory
Mary O'Reilly, Ph.D.
 
The Scripps Research Institute
10550 North Torrey Pines Road, MEM-L71
La Jolla, CA 92037
858-784-9646(phone)
858-784-9690 (FAX)
e-mail: moreilly@scripps.edu

EDUCATION:

March 2006 - Ph. D. Chemistry Program, Massachusetts Institute of Technology, Cambridge, MA (USA)

May 1999 - B.S. in Chemistry, Purdue University, West Lafayette, IN (USA)



PROFESSIONAL EXPERIENCES:

2006 to Present - Postdoctoral Fellow, The Scripps Research Institute, La Jolla, CA, USA. (Advisor: Prof. James C. Paulson)

2000-2005 - Research Assistant, Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA (Advisor: Prof. Barbara Imperiali)

2003 - Industrial Internship for two months, New England Biolabs, Inc. , USA (Advisor: Dr. Francine Perler)

1997-1999 - Research Assistant, Department of Chemistry, Purdue University, West Lafayette, IN, USA (Advisor: Prof. Jean Chmielewski)

1997 - DResearch Assistant, Department of Chemistry, Purdue University, West Lafayette, IN, USA (Advisor: Prof. Bruce Morimoto)



ACADEMIC AND PROFESSIONAL HONORS:

July 2007-June 2010 : Fellowship grant with American Cancer Society

Summer 2001-Summer 2004 : Biotechnology Training Grant with National Institutes of Health

Fall 2000 : Chemistry department award for outstanding teaching by a graduate student at Massachusetts Institute of Technology

Spring 1999 : Dale W. Margerum Undergraduate Research Scholarship with Purdue University

Spring 1999 : Iota Sigma Pi Chemistry Department outstanding senior woman award at Purdue University



PUBLICATIONS:

O'Reilly, M.K.; Collins, B.E.; Han, S.; Liao, L.; Rillahan, C.; Kitov, P.I.; Bundle, D.R.; Paulson, J.C. Bi-functional CD22 ligands use multimeric immunoglobulins as protein scaffolds in assembly of immune complexes on B cells. J. Am. Chem. Soc. 2008 In press.

Kaltgrad, E.; O'Reilly, M.K.; Liao, L., Han, S.; Paulson, J.C.; Finn, M.G. On-Virus Construction of Polyvalent Glycan Ligands for Cell-Surface Receptors. J. Am. Chem. Soc. 2008 130(14), 4578.

O'Reilly, M.K.; Zhang, G. Z.; Imperiali, B. In Vitro Evidence for the Dual Function of Alg2 and Alg11: Essential Mannosyltransferases in N-linked Glycoprotein Biosynthesis. Biochemistry 2006 45, 9593.

Hackenberger, C.P.; O'Reilly, M.K.; Imperiali, B. Improving Glycopeptide Synthesis: a Convenient Protocol for the Preparation of beta-Glycosylamines and the Synthesis of Glycopeptides. J. Org. Chem. 2005 70(9), 3574.

Zhao, L.; O'Reilly, M.K.; Shultz, M.D.; Chmielewski, J. Interfacial Peptide Inhibitors of HIV-1 Integrase Activity and Dimerization. Bioorg. Med. Chem. Lett. 2003 13(6), 1175.

Peluso, S.; Ufret, M.D.; O'Reilly, M.K.; Imperiali, B. Neoglycopeptides as Inhibitors of Oligosaccharyl Transferase: Insight into Negotiating Product Inhibition. Chem. Biol. 2002 9(12), 1323.

Tai, W.-F.V.; O'Reilly, M.K.; Imperiali, B. Substrate Specificity of N-Acetylglucosaminyl Diphosphodolichyl N-Acetylglucosaminyl Transferase, a Key Enzyme in the Dolichol Pathway. Bioorg. Med. Chem. 2001 9(5), 1173.


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