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Research Areas
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Detection of & Protection
from Warfare Agents
Biochemical Reactivity
of Drugs of Abuse
Catalytic Antibodies
Bacterial Cell-Cell Communication
Phage Display Technology
Drug Addiction & Abuse: Immunopharmacotherapy
Environmental Detection
of Heavy Metals
General Organic Synthesis
Combinatorial Chemistry & Polymer Synthesis
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Authors, Title
Journal, Volume, Pages, (Year)
372
Zhou, B., Pellett, S., Tepp, W.H., Zhou, H., Johnson, E.A., Janda, K.D., "Delineating the susceptibility of botulinum neurotoxins to denaturation through thermal effects"
FEBS Letters, 582, 1526 (2008)
369
Zhou, B., Carney, C., Janda, K.D., "Selection and characterization of human antibodies neutralizing Bacillus anthracis toxin"
Bioorg. Med. Chem., 16, 1903 (2008)
366
Zarebski, L.M., Vaughan, K., Sidney, J., Peters, B., Grey, H., Janda, K.D., Casadevall, A., Sette, A., "Analysis of epitope information related to Bacillus anthracis and Clostridium botulinum"
Expert Rev. Vaccines, 7(1), 55 (2008)
362
Zhou, H., Zhou, B., Ma, H., Carney, C., Janda, K.D., "Selection and characterization of human monoclonal antibodies against Abrin by phage display"
Bioorg. Med. Chem. Lett., 17, 5690 (2007)
360
Capcova, K., Yoneda, Y., Dickerson, T.J., Janda, K.D., "Synthesis and structure-activity relationships of second-generation hydroxymate botulinum neurotoxin A protease inhibitors"
Bioorg. Med. Chem. Lett., 17, 6463 (2007)
356
Dickerson, T.J., Janda, K.D., "The use of small molecules to investigate molecular mechanisms and therapeutic targets for treatment of botulinum neurotoxin A intoxication"
Chem. Biol., 2(4), 359 (2007)
354
Silvaggi, N.R., Boldt, G.E., Hixon, M.S., Kennedy, J.P., Tzipori, S., Janda, K.D., "Structures of Clostridium botulinum neurotoxin serotype A light chain complexed with small-molecule inhibitors highlight active-site flexibility"
Chemistry & Biology, 14, 533 (2007)
353
Eubanks, L.E., Dickerson, T.J., Janda, K.D., "Technological advancements for the detection of and protection against biological and chemical warfare agents"
Chem. Soc. Rev., 36(3), 441 (2007)
347
Steiniger, S.C.J., Altobell III, L., Zhou, B., Janda, K.D., "Selection of human antibodies against cell surface-associated oligomeric anthrax protective antigen"
Molecular Immunology, 44, 2749 (2007)
346
Eubanks, L.M., Hixon, M.S., Jin, W., Hong, S., Clancy, C.M., Tepp, W.H., Baldwin, M.R., Malizio, C.J., Gooodnough, M.C., Barbieri, J.T., Johnson, E.A., Boger, D.L., Dickerson, T.J., Janda, K.D., "An in vitro and in vivo disconnect uncovered through high-throughput identification of botulinum neurotoxin A antagonists"
Proc. Natl. Acad. Sci. U.S.A., 104(8), 2602 (2007)
338
Dickerson, T.J., Janda, K.D., "The use of small molecules to investigate molecular mechanisms and therapeutic targets for treatment of botulinum neurotoxin A intoxication"
ACS Chemical Biology, 1 (6), 359 (2006)
337
Boldt, G.E., Eubanks, L.M., Janda, K.D., "Identification of a botulinum A protease inhibitor displaying efficacy in a cellular model"
Chem. Commun., 3063 (2006)
336
Ma, H., Zhou, B., Kim, Y., Janda, K.D., "A cyclic peptide-polymer probe for the detection of Clostridium botulinum neurotoxin serotype A"
Toxicon, 47, 901 (2006)
335
Fu, Z., Chen, S., Baldwin, M.R., Boldt, G.E., Crawford, A., Janda, K.D., Barbieri, J.T., Kim, J.-J.P., "Light chain of botulinum neurotoxin serotype A: Structural resolution of a catalytic intermediate"
Biochemistry, (2006)
334
Boldt, G.E., Kennedy, J.P., Hixon, M.S., Mcallister, L.A., Barbieri, J.T., Tzipori, S., Janda, K.D., "Synthesis, characterization and development of a high-throughput methodology for the discovery of botulinum neurotoxin A inhibitors"
J. Comb. Chem., 8, 513 (2006)
332
Boldt, G.E., Kennedy, J.P., Janda, K.D., "Identification of a potent botulinum nneurotoxin A protease inhibitor using in situ lead identification chemistry"
Org. Lett., 8, 1729 (2006)
329
McAllister, L.A., Hixon, M.S., Kennedy, J.P., Dickerson, T.J., Janda, K.D., "Superactivation of the botulinum neurotoxin serotype A light chain metalloprotease: A new wrinkle in botulinum neurotoxin"
J. Am. Chem. Soc., 128, 4176 (2006)
313
Eubanks, L.M., Dickerson, T.J., Janda, K.D., "Vitamin B2-mediated cellular photoinhibition of botulinum neurotoxin A"
FEBS Letters, 579, 5361 (2005)
230
Zhou, B., Wirsching, P., Janda, K.D., "Human antibodies against spores of the genus Bacillus: A model study for the detection of and protection against anthrax and the bioterrorist threat"
Proc. Nat. Acad. Sci., 99, 5421 (2002)
151
Ashley, J.A., Lin, C.-H., Wirsching, P., Janda, K.D., "Monitoring chemical warfare agents: A new method for the detection of methylphosphonic acid"
Angew. Chem. Int. Ed., 38, 1793 (1999)
93
Lavey, B.J., Janda, K.D., "Catalytic antibody mediated hydrolysis of paraoxon"
J. Org. Chem., 61, 7633 (1996)