Janda Group - Publications [Bacterial Cell-Cell Communication]

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	Research Areas


Full Listing	Detection of & Protection from Warfare Agents	Biochemical Reactivity of Drugs of Abuse

Catalytic Antibodies	Bacterial Cell-Cell Communication	Phage Display Technology

Drug Addiction & Abuse: Immunopharmacotherapy	Environmental Detection of Heavy Metals	General Organic Synthesis

Combinatorial Chemistry & Polymer Synthesis	Approaches for Cancer Therapy

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Authors, Title
Journal, Volume, Pages, (Year)

	371

Kaufmann, G.F., Park, J., Mee, J.M., Ulevitch, R.J., Janda, K.D., "The quorum quenching antibody RS2-1G9 protects macrophages from the cytotoxic effects of the Pseudomonas aeruginosa quorum sensing signalling molecule N-3-oxo-dodecanoyl-homoserine lactone"
Molecular Immunology, 45, 2710 (2008)

	361

Park, J., Jagasia, R., Kaufmann, G.F., Mathison, J.C., Ruiz, D.I., Moss, J.A., Meijler, M.M., Ulevitch, R.J., Janda, K.D., "Infection control by antibody disruption of bacterial quorum sensing signaling"
Chemistry & Biology, 14, 1119 (2007)

	355

Debler, E.W., Kaufmann,G.F., Kirchdoerfer, R.N., Mee, J.M., Janda, K.D., Wilson, I.A., "Crystal structures of a quorum-quenching antibody"
J. Mol. Biol., 368(5), 1392 (2007)

	350

De Lamo Marin, S., Xu, X., Meijler, M.M., Janda, K.D., "Antibody catalyzed hydrolysis of a quorum sensing signal found in Gram-negative bacteria"
Bioorg. Med. Chem. Lett., 17, 1549 (2007)

	343

Kravchenko, V.V., Kaufmann, G.F., Mathison, J.C., Scott, D.A., Katz, A.Z., Woood, M.R., Brogan, A.P., Lehmann, M., Mee, J.M., Iwata, K., Pan, Q., Fearns, C., Knaus, U.G., Meijler, M.M., Janda, K.D., Ulevitch, R.J., "N-(3-Oxo-acyl)homoserine llactones signal cell activation through a mechanism distinct from the canonical pathogen-associated molecular pattern recognition receptor pathways"
Journal of Biological Chemistry, 281(39), 28822 (2006)

	330

Kaufmann, G.F., Sartorio, R., Lee, S.-H., Mee, J.M., Altobell, III, L.J., Kujawa, D.P., Jeffries, E., Clapham, B., Meijler, M.M., Janda, K.D., "Antibody interference with N-acyl homoserine lactone-mediated bacterial quorum sensing"
J. Am. Chem. Soc., 128, 2802 (2006)

	327

Shigenaga, S., Moss, J.A., Ashley, F.T., Kaufmann, G.F., Janda, K.D., "Solid-phase synthesis and cyclative cleavage of quorum sensing depsipeptide analogues by acylphenyldiazene activation"
SYNLETT, 4, 551 (2006)

	311

McKenzie, K.M., Meijler, M.M., Lowery, C.A., Boldt, G.E., Janda, K.D., "A furanosyl-carbonate autoinducer in cell-to-cell communication of V. harveyi"
Chem. Commun., 4863 (2005)

	302

Lowery, C.A., McKenzie, K.M., Qi, L., Meijler, M.M., Janda, K.D., "Quorum sensing in Vibrio harveyi: probing the specificity of the LuxP binding site"
Bioorg. Med. Chem. Lett., 15, 2395 (2005)

	294

Kaufmann, G.F., Sartorio, R., Lee, S.-H., Rogers, C.J., Meijler, M.M., Moss, J.A., Clapham, B., Brogan, A.P., Dickerson, T.J., Janda, K.D., "Revisiting quorum sensing: Discovery of additional chemical and biological functions for 3-oxo-N-acylhomoserine lactones"
Proc. Natl. Acad. Sci. USA, 102(2), 309 (2005)

	277

Meijler, M.M., Hom, L.G., Kaufmann, G.F., McKenzie, K.M., Sun, C., Moss, J.A., Matsushita, M., Janda, K.D., "Synthesis and biological validation of a ubiquitous quorum-sensing molecule"
Angew. Chem. Int. Ed., 43, 2106 (2004)

	222

Matsushita, M., Janda, K.D., "Histidine kinases as targets for new antimicrobial agents"
Bioorg. Med. Chem., 10, 855 (2002)