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Authors, Title Journal, Volume, Pages, (Year) |
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Zhou, B., Pellett, S., Tepp, W.H., Zhou, H., Johnson, E.A., Janda, K.D., "Delineating the susceptibility of botulinum neurotoxins to denaturation through thermal effects" FEBS Letters, 582, 1526 (2008) |
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Kaufmann, G.F., Park, J., Mee, J.M., Ulevitch, R.J., Janda, K.D., "The quorum quenching antibody RS2-1G9 protects macrophages from the cytotoxic effects of the Pseudomonas aeruginosa quorum sensing signalling molecule N-3-oxo-dodecanoyl-homoserine lactone" Molecular Immunology, 45, 2710 (2008) |
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Yoneda, Y., Steiniger, S.C.J., Capkova, K., Mee, J.M., Liu, Y., Kaufmann, G.F., Janda, K.D., "A cell-penetrating peptidic GRP78 ligand for tumor cell-specific prodrug therapy" Bioorg. Med. Chem. Lett., 18, 1632 (2008) |
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Zhou, B., Carney, C., Janda, K.D., "Selection and characterization of human antibodies neutralizing Bacillus anthracis toxin" Bioorg. Med. Chem., 16, 1903 (2008) |
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Meijler, M.M., Kaufmann, G.F., Qi, L., Mee, J.M., Coyle, A.R., Moss, J.A., Wirsching, P., Matsushita, M., Janda, K.D., "Fluorescent cocaine probes: A tool for the selection and engineering of therapeutic antibodies" J. Am. Chem. Soc., 127, 2477 (2005) |
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Willis, B., Eubanks, L.M., Wood, M.R., Janda, K.D., Dickerson, T.J., Lerner, R.A.L., "Biologically templated organic polymers with nanoscale order" PNAS, 105(5), 1416 (2008) |
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Zarebski, L.M., Vaughan, K., Sidney, J., Peters, B., Grey, H., Janda, K.D., Casadevall, A., Sette, A., "Analysis of epitope information related to Bacillus anthracis and Clostridium botulinum" Expert Rev. Vaccines, 7(1), 55 (2008) |
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Dickerson, T.J., Janda, K.D., "Recent advances for the treatment of cocaine abuse: Central nervous system immunopharmacotherapy" The AAPS Journal, 7(3), E579 (2005) |
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Brogan, A.P., Dickerson, T.J., Janda, K.D., "Nornicotine-organocatalyzed aqueous reduction of alpha, beta-unsaturated aldehydes" Chem. Commun., 46, 4952 (2007) |
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Richardson, H.N., Zhao, Y., Fekete, E.M., Funk, C.K., Wirsching, P., Janda, K.D., Zorrilla, E.P., Koob, G.F., "MPZP: A novel small molecule corticotropin-releasing factor type 1 receptor (CRF1) antagonist" Pharmacology, Biochemistry, and Behavior, 88, 497 (2007) |
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Zhou, H., Zhou, B., Ma, H., Carney, C., Janda, K.D., "Selection and characterization of human monoclonal antibodies against Abrin by phage display" Bioorg. Med. Chem. Lett., 17, 5690 (2007) |
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Park, J., Jagasia, R., Kaufmann, G.F., Mathison, J.C., Ruiz, D.I., Moss, J.A., Meijler, M.M., Ulevitch, R.J., Janda, K.D., "Infection control by antibody disruption of bacterial quorum sensing signaling" Chemistry & Biology, 14, 1119 (2007) |
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Capcova, K., Yoneda, Y., Dickerson, T.J., Janda, K.D., "Synthesis and structure-activity relationships of second-generation hydroxymate botulinum neurotoxin A protease inhibitors" Bioorg. Med. Chem. Lett., 17, 6463 (2007) |
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Xu, Y., Hixon, M.S., Dawson, P.E., Janda, K.D., "Development of o FRET assay for monitoring of HIV gp41 core disruption" J. Org. Chem., 72(18), 6700 (2007) |
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Treweek, J., Wee, S., Koob, G.F., Dickerson, T.J., Janda, K.D., "Self-vaccination by methamphetamine glycation products chemically links chronic drug abuse and cardiovascular disease" PNAS, 104(28), 11580 (2007) |
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Ino, A., Dickerson, T.J., Janda, K.D., "Positional linker effects in haptens for cocaine immunopharmacotherapy" Bioorg. Med. Chem. Lett., 17, 4280 (2007) |
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Dickerson, T.J., Janda, K.D., "The use of small molecules to investigate molecular mechanisms and therapeutic targets for treatment of botulinum neurotoxin A intoxication" Chem. Biol., 2(4), 359 (2007) |
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Debler, E.W., Kaufmann,G.F., Kirchdoerfer, R.N., Mee, J.M., Janda, K.D., Wilson, I.A., "Crystal structures of a quorum-quenching antibody" J. Mol. Biol., 368(5), 1392 (2007) |
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Silvaggi, N.R., Boldt, G.E., Hixon, M.S., Kennedy, J.P., Tzipori, S., Janda, K.D., "Structures of Clostridium botulinum neurotoxin serotype A light chain complexed with small-molecule inhibitors highlight active-site flexibility" Chemistry & Biology, 14, 533 (2007) |
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Eubanks, L.E., Dickerson, T.J., Janda, K.D., "Technological advancements for the detection of and protection against biological and chemical warfare agents" Chem. Soc. Rev., 36(3), 441 (2007) |
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Liu, Y., Steiniger, S.C.J., Kim, Y., Kaufmann, G.F., Felding-Habermann, B., Janda, K.D., "Mechanistic studies of a peptidic GRP78 ligand for cancer celll-specific drug delivery" Molecular Pharmaceutics, 4(3), 435 (2007) |
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Brogan, A.P., Eubanks, L.M., Koob, G.F., Dickerson, T.J., Janda, K.D., "Antibody-catalyzed oxidation of delta-9-tetrahydrocannabinol" J. Am. Chem. Soc., 129, 3698 (2007) |
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De Lamo Marin, S., Xu, X., Meijler, M.M., Janda, K.D., "Antibody catalyzed hydrolysis of a quorum sensing signal found in Gram-negative bacteria" Bioorg. Med. Chem. Lett., 17, 1549 (2007) |
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McAllister, L.A., Hixon, M.S., Schwartz, R., Kubitz, D.S., Janda, K.D., "Synthesis and application of a novel ligand for affinity chromatography based removal of endotoxin from antibodies" Bioconj. Chem., 18, 559 (2007) |
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Xu, Y., Hixon, M.S., Yamamoto, N., McAllister, L.A., Wentworth, A.D., Wentworth, Jr., P., Janda, K.D., "Antibody-catalyzed anaerobic destruction of methamphetamine" PNAS, 104(10), 3681 (2007) |
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Steiniger, S.C.J., Altobell III, L., Zhou, B., Janda, K.D., "Selection of human antibodies against cell surface-associated oligomeric anthrax protective antigen" Molecular Immunology, 44, 2749 (2007) |
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Eubanks, L.M., Hixon, M.S., Jin, W., Hong, S., Clancy, C.M., Tepp, W.H., Baldwin, M.R., Malizio, C.J., Gooodnough, M.C., Barbieri, J.T., Johnson, E.A., Boger, D.L., Dickerson, T.J., Janda, K.D., "An in vitro and in vivo disconnect uncovered through high-throughput identification of botulinum neurotoxin A antagonists" Proc. Natl. Acad. Sci. U.S.A., 104(8), 2602 (2007) |
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Rogers, C.J., Eubanks, L.M., Dickerson, T.J., Janda, K.D., "Unexpected acetylcholinesterase activity of cocaine esterases" J. Am. Chem. Soc., 128, 15364 (2006) |
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McKenzie, K.M., Mee, J.M., Rogers, C.J., Hixon, M.S., Kaufmann, G.F., Janda, K.D., "Identification and characterization of single chain anti-cocaine catalytic antibodies" J.Mol. Bio., 365, 722 (2006) |
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Kravchenko, V.V., Kaufmann, G.F., Mathison, J.C., Scott, D.A., Katz, A.Z., Woood, M.R., Brogan, A.P., Lehmann, M., Mee, J.M., Iwata, K., Pan, Q., Fearns, C., Knaus, U.G., Meijler, M.M., Janda, K.D., Ulevitch, R.J., "N-(3-Oxo-acyl)homoserine llactones signal cell activation through a mechanism distinct from the canonical pathogen-associated molecular pattern recognition receptor pathways" Journal of Biological Chemistry, 281(39), 28822 (2006) |
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Eubanks, L.M., Rojers, C.J., Beuscher IV, A.E., Koob, G.F., Olson, A.J., Dickerson, T.J., Janda, K.D. , "A molecular link between the active component of marijuana and Alzheimer's disease pathology" Molecular Pharmaceutics, 3(6), 773 (2006) |
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Brogan, A.P., Dickerson, T.J., Janda, K.D., "Enamine-based aldol organocatalysis in water: Are they really "all wet"?" Angew. Chem. Int. Ed., 45, 8100 (2006) |
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Zorilla, E.P., Iwasaki, S., Moss, J.A., Chang, J., Otsuji, J., Inoue, K., Meijler, M.M., Janda, K.D., "Vaccination against weight gain" PNAS, 103(35), 13226 (2006) |
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Kim, Y., Lillo, A.M., Steiniger, S.C.J., Liu, Y., Ballatore, C., Anichini, A., Mortarini, R., Kaufmann, G.F., Zhou, B., Felding-Habermann, B., Janda, K.D., "Targeting heat shock protiens on cancer cells: Selection, characterization, and cell-penetrating properties of a peptidic GRP78 ligand" Biochemistry, 45 (31), 9434 (2006) |
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Dickerson, T.J., Janda, K.D., "The use of small molecules to investigate molecular mechanisms and therapeutic targets for treatment of botulinum neurotoxin A intoxication" ACS Chemical Biology, 1 (6), 359 (2006) |
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Boldt, G.E., Eubanks, L.M., Janda, K.D., "Identification of a botulinum A protease inhibitor displaying efficacy in a cellular model" Chem. Commun., 3063 (2006) |
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Ma, H., Zhou, B., Kim, Y., Janda, K.D., "A cyclic peptide-polymer probe for the detection of Clostridium botulinum neurotoxin serotype A" Toxicon, 47, 901 (2006) |
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Fu, Z., Chen, S., Baldwin, M.R., Boldt, G.E., Crawford, A., Janda, K.D., Barbieri, J.T., Kim, J.-J.P., "Light chain of botulinum neurotoxin serotype A: Structural resolution of a catalytic intermediate" Biochemistry, (2006) |
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Boldt, G.E., Kennedy, J.P., Hixon, M.S., Mcallister, L.A., Barbieri, J.T., Tzipori, S., Janda, K.D., "Synthesis, characterization and development of a high-throughput methodology for the discovery of botulinum neurotoxin A inhibitors" J. Comb. Chem., 8, 513 (2006) |
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Xu, Y., Lu, H., Kennedy, J.P., Yan, X., McAllister, L.A., Yamamoto, N., Moss, J.A., Boldt, G.E., Jiang, S., Janda, K.D., "Evaluation of "credit-card" libraries for inhibition of HIV-1 gp41 fusogenic core formation" J. Comb. Chem., 8, 531 (2006) |
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Boldt, G.E., Kennedy, J.P., Janda, K.D., "Identification of a potent botulinum nneurotoxin A protease inhibitor using in situ lead identification chemistry" Org. Lett., 8, 1729 (2006) |
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Xu, Y., Shi, J., Yamamoto, N., Moss, J.A., Vogt, P.K., Janda, K.D., "A credit-card library approach for disrupting protein-protein interactions" Bioorg. Med. Chem., 14, 2660 (2006) |
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Kaufmann, G.F., Sartorio, R., Lee, S.-H., Mee, J.M., Altobell, III, L.J., Kujawa, D.P., Jeffries, E., Clapham, B., Meijler, M.M., Janda, K.D., "Antibody interference with N-acyl homoserine lactone-mediated bacterial quorum sensing" J. Am. Chem. Soc., 128, 2802 (2006) |
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McAllister, L.A., Hixon, M.S., Kennedy, J.P., Dickerson, T.J., Janda, K.D., "Superactivation of the botulinum neurotoxin serotype A light chain metalloprotease: A new wrinkle in botulinum neurotoxin" J. Am. Chem. Soc., 128, 4176 (2006) |
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Zhu, X., Dickerson, T.J., Rogers, C.J., Kaufmann, G.F., Mee, J.M., McKenzie, K.M., Janda, K.D., Wilson, I.A., "Complete reaction cycle of a cocaine catalytic antibody at atomic resolution" Structure, 14, 205 (2006) |
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Shigenaga, S., Moss, J.A., Ashley, F.T., Kaufmann, G.F., Janda, K.D., "Solid-phase synthesis and cyclative cleavage of quorum sensing depsipeptide analogues by acylphenyldiazene activation" SYNLETT, 4, 551 (2006) |
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Moss, J.A., Stokols, S., Hixon, M.S., Ashley, F.T., Chang, J.Y., Janda, K.D., "Solid-phase synthesis and kinetic characterization of fluorogenic enzyme-degradable hydrogel cross-linkers" Biomacromolecules, 7, 1011 (2006) |
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Boldt, G.E., Dickerson, T.J., Janda, K.D., "Emerging chemical and biological approaches for the preparation of discovery libraries" Drug Disc. Today, 11, 143 (2006) |
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Rogers, C.J., Dickerson, T.J., Janda, K.D., "Kinetic isotope and thermodynamic analysis of the nornicotine-catalyzed aqueous aldol reaction" Tetrahedron, 62, 352 (2006) |
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Shimomura, O., Lee, B.S., Meth, S., Suzuki, H., Mahajan, S., Nomura, R., Janda, K.D., "Synthesis and application of polytetrahydrofuran-grafted polystyrene (PS-PTHF) resin supports for organic synthesis" Tetrahedron, 61, 12160 (2005) |
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Rogers, C.J., Dickerson, T.J., Wentworth, Jr.,P., Janda, K.D., "A high-swelling reagent scaffold suitable for use in aqueous and organic solvents" Tetrahedron, 61, 12140 (2005) |
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Zhang, L., Long, H., Boldt, G.E., Janda, K.D., Schatz, G.C., Lewis, F.D., "alpha- and beta-Stilbenosides as base-pair surrogates in DNA hairpins" Org. Biomol. Chem., 4, 314 (2006) |
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Wu, W., Luo, Y., Sun, C., Liu, Y., Kuo, P., Varga, J., Xiang, R., Reisfeld, R., Janda, K.D., Edgington, T.S., Liu, C., "Targeting cell-impermeable prodrug activation to tumor microenvironment eradicates multiple drug-resistant neoplasms" Cancer Res., 66(2), 1 (2006) |
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Kim, Y., Lillo, A., Moss, J.A., Janda, K.D., "A contiguous stretch of methionine residues mediates the energy-dependent internalization mechanism of a cell-penetrating peptide" Molecular Pharmaceutics, 2(6), 528 (2005) |
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Lillo, A.M., McKenzie, K.M., Janda, K.D., "Phage-Displayed Antibody Libraries" Cell Biology: A Laboratory Handbook, Chp. 59, 491-496 (2006) |
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Qi, L., Yamamoto, N., Meijler, M.M., Altobell, III, L.J., Koob, G.F., Wirsching, P., Janda, K.D., "Delta-9-tetrahydrocannabinol immunochemical studies: Haptens, monoclonal antibodies, and a convenient synthesis of radiolabeled delta-9-tetrahydrocannabinol" J. Med. Chem., 48, 7389 (2005) |
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Dickerson, T.J., Beuscher IV, A.E., Rogers, C.J., Hixon, M.S., Yamamoto, N., Xu, Y., Olson, A.J., Janda, K.D. , "Discovery of acetylcholinesterase peripheral anionic site ligands through computational refinement of a directed library" Biochemistry, 44, 14845 (2005) |
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Shute, T.S., Matsushita, M., Dickerson, T.J., La Clair, J.J., Janda, K.D., Burkart, M.D., "A site-specific bifunctional protein labeling system for affinity and fluorescent analysis" Bioconjugate Chem., 16, 1352 (2005) |
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Matsushita, M., Meijler, M.M., Wirsching, P., Lerner, R.A., Janda, K.D., "A blue fluorescent antibody-cofactor sensor for mercury" Org. Lett., 7, 4943 (2005) |
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Eubanks, L.M., Dickerson, T.J., Janda, K.D., "Vitamin B2-mediated cellular photoinhibition of botulinum neurotoxin A" FEBS Letters, 579, 5361 (2005) |
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Carrera, M.R.A., Trigo, J.M., Wirsching,P., Roberts, A.J., Janda, K.D., "Evaluation of the anticocaine monoclonal antibody GNC92H2 as an immunotherapy for cocaine overdose" Pharmacology, Biochemistry and Behavior, 81, 709 (2005) |
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McKenzie, K.M., Meijler, M.M., Lowery, C.A., Boldt, G.E., Janda, K.D., "A furanosyl-carbonate autoinducer in cell-to-cell communication of V. harveyi" Chem. Commun., 4863 (2005) |
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Toker, J.D., Tremblay, M.R., Yli-Kauhaluoma, J., Wentworth, A.D., Zhou, B., Wentworth, Jr., P., Janda, K.D., "Exploring the scope of the 29G12 antibody catalyzed 1,3-dipolar cycloaddition reaction" J. Org. Chem., 70, 7810 (2005) |
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Xu, Y., Yamamoto, N., Ruiz, D.I., Kubitz, D.S., Janda, K.D., "Squaric monoamide monoester as a new class of reactive immunization hapten for catalytic antibodies" Bioorg. Med. Chem. Lett., 15, 4304 (2005) |
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Yamashita, M., Lee, S.-H., Koch, G., Zimmermann, J., Clapham, B., Janda, K.D., "Solid-phase synthesis of oxazolones and other heterocycles via Wang resin-bound diazocarbonyls" Tetrahedron Lett., 46, 5495 (2005) |
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Rogers, C.J., Mee, J.M., Kaufmann, G.F., Dickerson, T.J., Janda, K.D., "Toward cocaine esterase therapeutics" J. Am. Chem. Soc., 127(28), 10016 (2005) |
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Brogan, A.P., Dickerson, T.J., Boldt, G.E., Janda, K.D., "Altered retinoid homeostasis catalyzed by a nicotine metabolite: Implications in macular degeneration and normal development" Proc. Natl. Acad. Sci. U.S.A., 102(30), 10433 (2005) |
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Lee, B.S., Mahajan, S., Janda, K.D., "Molecular iodine-catalyzed imine activation for three-component nucleophilic addition reactions" Synlett, 8, 1325 (2005) |
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Lee,B.S., Mahajan, S., Janda, K.D., "Asymmetric dihydroxylation catalyzed by ionic polymer-supported osmium tetroxide" Tetrahedron Lett., 46, 4491 (2005) |
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Dickerson, T.J., Kaufmann, G.F., Janda, K.D., "Bacteriophage-mediated protein delivery into the central nervous system and its application in immunopharmacotherapy" Expert Opin. Biol. Ther., 5(6), 773 (2005) |
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Lowery, C.A., McKenzie, K.M., Qi, L., Meijler, M.M., Janda, K.D., "Quorum sensing in Vibrio harveyi: probing the specificity of the LuxP binding site" Bioorg. Med. Chem. Lett., 15, 2395 (2005) |
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Rogers, C.L., Dickerson, T.J., Brogan, A.P., Janda,K.D., "Hammett correlation of nornicotine analogues in the aqueous aldol reaction: Implications for green organocatalysis" J. Org. Chem., 70(9), 3705 (2005) |
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Zorrilla, E., Fekete, E., Mason, B.J., Wirsching, P., Janda, K.D., "CRF1 antagonists for anxiety" European Neuropsychopharmacology, 13 (Suppl. 4), s130 (2003) |
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Kaufmann, G.F., Meijler, M.M., Sun, C., Chen, D.-W., Kujawa, D.P., Mee, J.M., Hoffman, T.Z., Wirsching, P., Lerner, R.A., Janda, K.D., "Enzymatic incorporation of an antibody-activated blue fluorophore into DNA" Angew. Chem. Int. Ed., 44, 2144 (2005) |
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Lee, B.S., Mahajan, S., Janda, K.D., "Cross-linked poly(4-vinylpyridine/styrene) copolymers as a support for immobilization of ytterbium triflate" Tetrahedron, 61, 3081 (2005) |
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Reed, N.N., Dickerson, T.J., Boldt, G.E., Janda, K.D., "Enantioreversal in the Sharpless asymmetric epoxidation reaction controlled by the molecular weight of a covalently appended achiral polymer" J. Org. Chem., 70(5), 1728 (2005) |
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Moss, J.A., Lillo, A., Kim, Y.S., Gao, C., Ditzel, H., Janda, K.D., "A dimerization 'switch' in the internalization mechanism of a cell-penetrating peptide" J. Am. Chem. Soc., 127, 538 (2005) |
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Lee, B.S., Mahajan, S., Janda, K.D., "Novel method for catalyst immobilization using an ionic polymer: A case study using recyclable yttterbium triflate" Tetrahedron Letters, 46, 807 (2005) |
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Kaufmann, G.F., Sartorio, R., Lee, S.-H., Rogers, C.J., Meijler, M.M., Moss, J.A., Clapham, B., Brogan, A.P., Dickerson, T.J., Janda, K.D., "Revisiting quorum sensing: Discovery of additional chemical and biological functions for 3-oxo-N-acylhomoserine lactones" Proc. Natl. Acad. Sci. USA, 102(2), 309 (2005) |
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Felding-Habermann, B., Lerner, R.A., Lillo, A., Zhuang, S., Weber, M.R., Arrues, S., Gao, C., Mao, S., Saven, A., Janda, K.D., "Combinatorial antibody libraries from cancer patients yield ligand mimetic Arg-Gly-Asp-containing immunoglobulins that inhibit breast cancer metastasis" Proc. Natl. Acad. Sci. USA, 101(49), 17210 (2004) |
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Dickerson, T.J., Reed, N.N., La Clair, J.J., Janda, K.D., "A precipitator for the detection of thiophilic heavy metals in aqua" J. Am. Chem. Soc., 126(50), 16582 (2004) |
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Lee, S.-H., Yoshida, K., Matsushita, H., Clapham, B., Koch, G., Zimmermann, J., Janda, K.D., "N-H insertion reactions of primary ureas: The synthesis of highly substituted imidazolones and imidazoles | |