Molecular Parasitology Meeting Abstracts

2008

Dharia N, Westenberger S, Sidhu A, Eastman R, Plouffe D, Bacon D, Espinosa B, Fidock D, Winzeler E. Elucidating mechanisms of drug resistance and determining population genetic structures in P. falciparum using high-density microarrays. [ Abstract 167B ]

Eastman R, Dharia N, Winzeler E, Fidock D. In vitro selection of piperaquine resistant Plasmodium falciparum. [ Abstract 129C ]

Kumar S, Young J, Ren B, Winzeler E. Genome-wide analyses of transcription regulatory elements and the transcription factors in Plasmodium falciparum. [ Abstract 107B ]

McNamara C, Plouffe D, Kuhen K, Henson K, Chen Z, Downs R, Chatterjee A, Winzeler E. A path forward to identify inhibitors of Plasmodium falciparum GTP-cyclohydrolase. [ Abstract 147B ]

Plouffe D, Rines D, Brusch III R, Kuhen K, Henson K, Chen Z, Downs R, Chatterjee A, Nagle A, Wu T, Sakata T, Winzeler E. Plasmodium chemical biology: Characterizing the mechanisms in which small molecules are inhibiting parasite proliferation for antimalarial drug development. [ Abstract 113B ]

Ramachandran V, Bopp S, Wiltshire T, Waters A, Winzeler E. Susceptibility or resistance to P. berghei in inbred mouse strains. [ Abstract 107A ]

Refour P, Westenberger S, Zhou Y, Merrick C, Winzeler E, Duraisingh M. Comparative transcriptomics of the asexual cycle in two closely related malaria parasites. [ Abstract 104B ]

Westenberger S, McClean C, Dharia N, Zhou Y, Barnwell J, Hoffman S, Vinetz J, Winzeler E. Plasmodium vivax transcriptome analysis of blood stages, gametocytes and sporozoites reveals significant divergence from P. falciparum and P. yoelii. [ Abstract 106B ]

2007

Dharia N, Westenberger S, Winzeler E. Globally identifying mutations in Plasmodium falciparum using high-density tiling microarrays. [ Abstract 208A ]

Kato N, Le Roch K, Sakata T, Nagle A, McNamara C, Plouffe D, Ward G, Gray N, Harper J, Winzeler E. Combined chemical and genomic characterization of a Plasmodium falciparum calcium-dependent protein kinase reveals a role in invasion. [ Abstract 5H ]

Westenberger S, Dharia N, Winzeler E. Comparative genome hybridization and gene expression profiling using Plasmodium vivax whole genome tiling microarrays. [ Abstract 203B ]

2006

Ramachandran V, Henson K, Spooner M, Luzadar A, Wiltshire T, Waters A, Winzeler E. Malaria susceptibility or resistance to inbred strains of mice.

Westenberger S, Kidgell C, Winzeler E. Identification of potential drug-resistance loci in Plasmodium species using microarray-based allelic variation scanning.

2005

Carret C, Qureshi M, Horrocks P, Konfortov B, Winzeler E, Newbold C, Ivens A. New tools for microarray-based CGH in Plasmodium falciparum.

Daily J, Le Roch K, Ndiaye D, Ndir O, Mboup S, Winzeler E, Wirth D. Variation of P. falciparum in vivo transcriptomes in patients with mild and severe disease

Johnson J, Le Roch K, Zhou Y, Henson K, Plouffe D, Yates J, Winzeler E. Non-coding genomics in P. falciparum.

2004

Carret C, Qureshi M, Horrocks P, Winzeler E, Newbold C, Berriman M, Ivens A. Genome-wide identification of a P. falciparum field isolate polymorphism / antigenic variation using genechip analysis.

Fivelman Q, Young J, Blair P, Le Roch K, Chen K, Yan S, Carucci D, Zhou Y, Winzeler E, Baker D. Sexual development of Plasmodium falciparum: Classification of a sexual stage specific gene expression cluster using ontology-based pattern identification.

Johnson J, Le Roch K, Florens L, Zhou Y, Santrosyan A, Grainger M, Williamson K, Holder A, Carucci D, Winzeler E, Yates J. Integrated analysis of mRNA and protein abundance in Plasmodium falciparum.

Le Roch K, Johnson J, Zhou Y, Henson K, Yates J, Vial H, Winzeler E. Functional genomics of the antimalarial choline analogue T4 on Plasmodium falciparum reveal potential therapeutic targets.

Kidgell C, Borevitz J, Johnson J, Volkman S, Plouffe D, Le Roch K, Wirth D, Zhou Y, Winzeler E. Genome-wide analysis of Plasmodium falciparum strains reveals novel polymorphic proteins under selection and identifies genetic heterogeneity within the parasite genome.

Young J, Zhou Y, Fivelman Q, Blair P, Le Roch K, Baker D, Carucci D, Winzeler E. Elucidation of Plasmodium falciparum gene function using ontology-based pattern identification.

2003

Le Roch K, Zhou Y, Blair P, Grainger M, Moch K, Haynes D, de la Vega P, Holder A, Batalov S, Carucci D, Winzeler E. Highly-parallel discovery of gene function by expression profiling of the malaria parasite lifecycle.

Stubbs J, Duraisingh M, Triglia T, Simpson K, Speed T, Winzeler E, Cowman A. Genes involved in sialic acid independent invasion of human erythrocytes by the malaria parasite.

2002

Le Roch K, Zhou Y, Batalov S, Grunenfelder B, Winzeler E. Transcriptome variations during the progression of the Plasmodium erythrocytic cell cycle: A genome-wide study using high-density oligonucleotide arrays.

Volkman S, Zhou Y, Nielsen K, Barry A, Batalov S, Lyons E, Le Roch K, Choi M, Oshiro G, Abagyan R, Day K, Hartl D, Winzeler E, Wirth D. Genome analysis of polymorphisms in Plasmodium falciparum.