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| Patapoutian | |
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Selected publications: Grandl J, Hu H, Bandell M, Bursulaya B, Schmidt M, Petrus M, Patapoutian A.
Pore region of TRPV3 ion channel is specifically required for heat activation.
Nat Neurosci. 2008 Aug 10;11:1007-13.
Dhaka A, Earley TJ, Watson J, Patapoutian A.
Visualizing cold spots: TRPM8-expressing sensory neurons and their projections.
J Neurosci. 2008 Jan 16;28(3):566-75.
Petrus M, Peier AM, Bandell M, Hwang SW, Huynh T, Olney N, Jegla T, Patapoutian A.
A role of TRPA1 in mechanical hyperalgesia is revealed by pharmacological inhibition.
Mol Pain. 2007 Dec 17;3:40.
Macpherson LJ, Xiao B, Kwan KY, Petrus MJ, Dubin AE, Hwang S, Cravatt B, Corey DP, Patapoutian A.
An ion channel essential for sensing chemical damage.
J Neurosci. 2007 Oct 17;27(42):11412-5.
Bandell M, Macpherson LJ, Patapoutian A.
From chills to chilis: mechanisms for thermosensation and chemesthesis via thermoTRPs.
Curr Opin Neurobiol. 2007 Aug;17(4):490-7.
Dhaka A, Murray AN, Mathur J, Earley TJ, Petrus MJ, Patapoutian A.
TRPM8 is Required for Cold Sensation in Mice. Neuron. 2007 May;54:371-8.
Kindt KS, Viswanath V, Macpherson L, Quast K, Hu H, Patapoutian A, Schafer WR.
Caenorhabditis elegans TRPA-1 functions in mechanosensation.
Nat Neurosci. 2007 May;10(5):568-77.
Macpherson LJ, Dubin AE, Evans MJ, Marr F, Schultz PG, Cravatt BF, Patapoutian A.
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines.
Nature. 2007 Feb 1;445(7127):541-5.
Macpherson LJ, Hwang SW, Miyamoto T, Dubin AE, Patapoutian A, Story GM.
More than cool: promiscuous relationships of menthol and other sensory compounds.
Mol Cell Neurosci. 2006 Aug;32(4):335-43.
Dhaka A, Viswanath V, Patapoutian A.
Trp ion channels and temperature sensation.
Annu Rev Neurosci. 2006;29:135-61.
Bandell M, Dubin AE, Petrus MJ, Orth A, Mathur J, Hwang SW, Patapoutian A.
High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol.
Nat Neurosci. 2006 Apr;9(4):493-500.
Macpherson LJ, Geierstanger BH, Viswanath V, Bandell M, Eid SR, Hwang S, Patapoutian A.
The Pungency of Garlic: Activation of TRPA1 and TRPV1 in Response to Allicin.
Curr Biol. 2005 May 24;15(10):929-34.
Moqrich A, Hwang SW, Earley TJ, Petrus MJ, Murray AN, Spencer KS, Andahazy M, Story GM, Patapoutian A.
Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin.
Science. 2005 Mar 4;307(5714):1468-72.
Moqrich A, Earley TJ, Watson J, Andahazy M, Backus C, Martin-Zanca D, Wright DE, Reichardt LF, Patapoutian A.
Expressing TrkC from the TrkA locus causes a subset of dorsal root ganglia neurons to switch fate.
Nat Neurosci. 2004 Aug;7(8):812-8.
Bandell M, Story GM, Hwang SW, Viswanath V, Eid SR, Petrus MJ, Earley TJ, Patapoutian A.
Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin.
Neuron. 2004 Mar 25;41(6):849-57.
Patapoutian A, Peier AM, Story GM, Viswanath V.
ThermoTRP channels and beyond: mechanisms of temperature sensation.
Nat Rev Neurosci. 2003 Jul;4(7):529-39.
Viswanath V, Story GM, Peier AM, Petrus MJ, Lee VM, Hwang SW, Patapoutian A, Jegla T.
Opposite thermosensor in fruitfly and mouse.
Nature. 2003 Jun 19;423(6942):822-3.
Story GM, Peier AM, Reeve AJ, Eid SR, Mosbacher J, Hricik TR, Earley TJ, Hergarden AC, Andersson DA, Hwang SW, McIntyre P, Jegla T, Bevan S, Patapoutian A.
ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures.
Cell. 2003 Mar 21;112(6):819-29.
Peier AM, Reeve AJ, Andersson DA, Moqrich A, Earley TJ, Hergarden AC, Story GM, Colley S, Hogenesch JB, McIntyre P, Bevan S, Patapoutian A.
A heat-sensitive TRP channel expressed in keratinocytes.
Science. 2002 Jun 14;296(5575):2046-9.
Peier AM, Moqrich A, Hergarden AC, Reeve AJ, Andersson DA, Story GM, Earley TJ, Dragoni I, McIntyre P, Bevan S, Patapoutian A.
A trp channel that senses cold stimuli and menthol.
Cell. 2002 Mar 8;108:705-15.
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TRP family of cation channels
A sprig of mint and its active cooling agent |
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