TSRI Logo

McLachlan Laboratory
Laboratory Home | Research | Publications | Personnel

Recent Publications

Tang, H. and McLachlan, A. Avian and mammalian hepadnaviruses have distinct transcription factor requirements for viral replication. J.Virol., 76, 7468-7472, 2002. View Publication

Tang, H. and McLachlan, A. A pregenomic RNA sequence adjacent to DR1 and complementary to epsilon determines hepatitis B virus replication efficiency. Virology, 303, 199-210, 2002. View Publication

Tang, H. and McLachlan, A. Mechanisms of inhibition of nuclear hormone receptor dependent hepatitis B virus replication by hepatocyte nuclear factor 3b. J.Virol., 76, 8572-8581, 2002. View Publication

Banks, K.E., Anderson, A.L., Tang, H., Hughes, D.E., Costa, R.H. and McLachlan, A. Hepatocyte nuclear factor 3b inhibits hepatitis B virus replication in vivo. J.Virol., 76, 12974-12980, 2002. View Publication

Alcantara, F., Tang, H. and McLachlan, A. Functional characterization of the interferon regulatory element in the enhancer 1 region of the hepatitis B virus genome. Nucleic Acids Res., 30: 2068-2075, 2002. View Publication

Tang, H., Raney, A.K. and McLachlan A. Replication of wild type and a natural hepatitis B virus nucleocapsid promoter variant is differentially regulated by nuclear hormone receptors in cell culture. J.Virol., 75, 8937-8948, 2001. View Publication

Raney, A.K., Kline, E.F., Tang, H. and McLachlan A. Transcription and replication of a natural hepatitis B virus nucleocapsid promoter variant is regulated in vivo by peroxisome proliferators. Virology, 289, 239-251, 2001. View Publication

Tang, H., Banks, K.E., Anderson, A.L. and McLachlan, A. Hepatitis B virus transcription and replication. Drug News Perspectives, 14, 325-334, 2001. View Publication

Raney, A.K., Eggers, C.M., Kline, E.F., Guidotti, L.G., Pontoglio, M., Yaniv, M. and McLachlan, A. Nuclear covalently closed circular viral genomic DNA in the liver of hepatocyte nuclear factor 1a-null hepatitis B virus transgenic mice. J.Virol., 75, 2900-2911, 2001. - PubMed Abstract

Tang, H. and McLachlan, A. Transcriptional regulation of hepatitis B virus by nuclear hormone receptors is a critical determinant of viral tropism. Proc. Natl. Acad. Sci. USA, 98, 1841-1846, 2001. - PubMed Abstract

Guidotti, L.G., Eggars, C.M., Raney, A.K., Chi, S.Y., Peters, J.M., Gonzalez, F.J. and McLachlan, A. In vivo regulation of hepatitis B virus replication by peroxisome proliferators. J.Virol., 73: 10377-10386, 1999. - PubMed Abstract

Raney, A.K., and McLachlan, A. Characterization of the hepatitis B virus major surface antigen promoter hepatocyte nuclear factor 3 binding site. J.Gen.Virol., 78: 3029-3038, 1997. - PubMed Abstract

Raney, A.K., Johnson, J.L., Palmer, C.N.A. and McLachlan, A. Members of the nuclear receptor superfamily regulate transcription from the hepatitis B virus nucleocapsid promoter. J.Virol., 71: 1058-1071, 1997. - PubMed Abstract

Raney, A.K., Zhang, P. and McLachlan, A. Regulation of transcription from the hepatitis B virus large surface antigen promoter by hepatocyte nuclear factor 3. J.Virol., 69: 3265-3272, 1995. - PubMed Abstract

Raney, A.K. and McLachlan, A. Characterization of the hepatitis B virus large surface antigen promoter Sp1 transcription factor binding site. Virology, 208: 399-404, 1995. - Virology Abstract

Johnson, J.L., Raney, A.K. and McLachlan, A. Characterization of a functional hepatocyte nuclear factor 3 binding site in the hepatitis B virus nucleocapsid promoter. Virology, 208: 147-158, 1995. - Virology Abstract

Raney, A.K., Easton, A.J. and McLachlan, A. Characterization of the minimal elements of the hepatitis B virus large surface antigen promoter. J. Gen. Virol., 75: 2671-2679, 1994. - PubMed Abstract

Zhang, P. and McLachlan, A. Differentiation-specific transcriptional regulation of the hepatitis B virus nucleocapsid gene in human hepatoma cell lines. Virology, 202: 430-440, 1994. - PubMed Abstract