1

Selected Publications

1995-2008:

Peter, F., Rowe, T., Nuoffer, C., Tisdale, E.J., Dascher, C., Schalk, E., Balch, W.E. (1995) Purification of His6-tagged Rab1 proteins using bacterial and insect cell expression systems, Expression and purification of mammalian Sar1a, Expression and purification of recombinant His6-tagged guanine nucleotide dissociation inhibitor and formation of Rab1 complex, Transient expression of small GTPases to study protein transport along secretory pathwa in vivo using recombinant T7 vaccinia virus system, Preparation of recombinant vaccinia virus for expression of small GTPases. In: Methods in Enzymology. Balch, W.E., Der, C., Hall, A. (Eds.). Academic Press, San Diego, p. 3, 49, 80, 165, 174.

Balch, W.E. and Farquhar, M.G. (1995) Beyond bulk flow. Trends in Cell Biol. 5:16-19.

Brown, W.J., Emr, S.D., Plutner , H. and Balch, W.E. (1995) Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells. J. Cell Biol. 130:781-796. (PubMed).

Simpson, J.C., Dascher, C., Roberts, L.M., Lord, J.M. and Balch, W.E. (1995) Ricin cytotoxicity is sensitive to recycling between the endoplasmic reticulum and the Golgi complex. J. Biol. Chem. 270:20078-20083.(PubMed).

Aridor, M., Bannykh, S.I., Rowe, T. and Balch, W.E. (1995) Sequential coupling between COPII and COPI vesicle coats in endoplasmic reticulum (ER) to Golgi transport. J. Cell Biol. 131:875-893. (PubMed).

Schalk, I., Zeng, K., Wu, S.-K., Stura, E.A., Matteson, J., Huang, M., Tandon, A., Wilson, I.A. and Balch, W.E. (1995) Structure and mutational analysis of Rab GDP-dissociation inhibitor. Nature 381:42-48. (PubMed).

Dascher, C. and Balch, W.E. (1996) Mammalian Sly1 regulates syntaxin 5 function in endoplasmic reticulum (ER) to Golgi transport. J. Biol. Chem. 271:15866-15869.(PubMed).

Bannykh, S., Aridor, M., Plutner, H., Rowe, T. and Balch, W.E. (1995) Regulated export of cargo from the endoplasmic reticulum of mammalian cells. Cold Spring Harbor Lab. Press, 60:127. (PubMed).

Aridor, M., Balch, W.E. (1996) Principles of selective transport: coat complexes hold the key. Trends Cell Biol. 6:315.

Wu, S.-K., Zeng, K., Wilson, I.A., Balch, W.E. (1996) The GDI-CHM/REP connection: structural insights into the Rab GTPase cycle. Trends Biochem. Sci., 21:472-476. (PubMed).

Tisdale, E.J. and Balch, W.E. (1996) Rab2 is essential for the assembly of pre-Golgi intermediates. J. Biol. Chem., 271:29372-29379.(PubMed).

Bannykh, S., Rowe, T. and Balch, W.E. (1996) The organization of endoplasmic reticulum export complexes. J. Cell Biol., 135:19-35. (PubMed).

Traub, L.M. , S.I. Bannykh, J.E. Rodel, M. Aridor, W.E. Balch and Kornfeld, S. (1996) AP-2-containing clathrin coats assemble on mature lysosomes. J. Cell Biol. 135:1801-1814. (PubMed).

Rowe, T., Aridor, M., McCaffery, J.M., Plutner, H. and Balch, W.E. (1996) COPII vesicles derived from mammalian endoplasmic reticulum (ER) microsomes recruit COPI. J. Cell Biol., 135:895-911.(PubMed).

Aridor, M. and Balch, W.E. (1996) Timing is everything. Nature 383: 220-221.

Tisdale, E.J., Plutner, H. Matteson, J., and Balch, W.E. (1997) p53/58: p53/58 binds COPI and is required for selective transport through the early secretory pathway. J. Cell Biol., 137:581-593.(PubMed).

Turner, M.D., Plutner, H. and Balch, W.E. (1997) A rab GTPase is required for homotypic assembly of the endoplasmic reticulum. J. Biol. Chem., 272:13479-13483.(PubMed).

Bannykh, S.I. and Balch, W.E. (1997) Membrane dynamics at the endoplasmic reticulum-Golgi interface. J Cell Biol., 138: 1-4.(PubMed).

Nuoffer, C., S.K. Wu, Dascher, C. and Balch, W.E. (1997) MSS4 does not function as an exchange factor for Rab in endoplasmic reticulum to Golgi transport. Mol. Biol. Cell 8: 1305-1316. (PubMed).

Rowe, T. and Balch, W.E. (1997) Membrane fusion. Bridging the gap by AAA ATPases. Nature 388: 20-21.(PubMed).

Nishimura, N. and Balch, W.E. (1997) A di-acidic signal required for selective export from the endoplasmic reticulum. Science 277: 556-558.(PubMed).

Bannykh, S.I., Nishimura, N. and Balch, W.E. (1998) Getting into the Golgi. Trends in Cell Biology 8:21-25.(PubMed).

Rowe, T., Dascher, C., Bannykh, S.I, Plutner, H. and Balch, W.E. (1998) Role of vesicle-associated syntaxin 5 in the assembly of pre-Golgi intermediates. Science 279:696-700. (PubMed).

Aridor, M., Weissman, J., Bannykh, S.I., Nuoffer, C. and Balch, W.E. (1998) Cargo selection by the COPII budding machinery during export from the endoplasmic reticulum. J. Cell Biol. 141:61-70. (PubMed).

Bannykh, S.I., Balch, W.E. (1998) Selective transport of cargo between the endoplasmic reticulum and Golgi compartments. Histochem. 109:463-475.(PubMed).

Tandon, A., Bannykh, S.I., Kowalchyk, J.A., Banerjee, A., Martin, T.F.J., Balch, W.E. (1998) Differential regulation of exocytosis by calcium and CAPS in semi-intact synaptosomes. Neuron 21:147-154.(PubMed).

D'Adamo. P., Menegon, A., Lo Nigro, C., Grasso, M., Gulisano, M., Tamanini, F., Bienvenu, T., Gedeon, A.K., Oostra, B., Wu, S.K., Tandon, A., Valtorta, F., Balch, W.E., Chelly, J., Toniolo, D. (1998) Mutations in GDI1 are responsible for x-linked non-specific mental retardation. Nature Genetics 19:134-139.(PubMed).

Wu, S.-K., Matteson, J., Zeng, K., Nishimura, N. and Balch, W.E. (1998) Molecular role for the rab binding pocket of guanine nucleotide dissociation inhibitor (GDI) in endoplasmic reticulum to Golgi transport. J. Biol. Chem. 273:26931-26938. (PubMed).

Aridor, M., Bannykh, S.I., Rowe, T. and Balch, W.E. (1998) Cargo Can Modulate COPII Vesicle Formation from the Endoplasmic Reticulum. J. Biol. Chem., 274:4389-4399. (PubMed).

Tandon, A., Tan, P.K., Bannykh, S.I., Banerjee, A. and Balch, W.E. (1998) Neurotransmitter release from semi-intact synaptosomes. Methods: A Companion to Methods in Enzymology 16:198.(PubMed).

Luan, P., Balch, W.E., Emr, S.D. and Burd, C.G. (1998) Molecular Dissection of Guanine Nucleotide Dissociation Inhibitor Function in Vivo. J. Biol. Chem. 274:14806-14817.(PubMed).

Allan, B.B. and Balch, W.E. (1998) In vitro analysis of endoplasmic reticulum to Golgi transport in mammalian cells. Current Protocols in Cell Biology, 11.3.1 — 11.3.22.

Aridor, M. and Balch, W.E. (1999) Integration of endoplasmic reticulum signaling in health and disease. Nature Medicine 5:745-751.(PubMed).

Allan, B.B. and Balch, W.E. (1999) Protein sorting by directed maturation of Golgi compartments. Science 285:63-66.(PubMed).

Luan, P., Balch, W.E., Emr, S.D. and Burd, C.G. (1999) Molecular Dissection of Guanine Nucleotide Dissociation Inhibitor Function in Vivo. J. Biol. Chem. 274:14806-14817.(PubMed).

Nishimura, N., Bannykh, S.I., Slabough, S., Matteson, J., Hahn, K. and Balch, W.E. (1999) A di-acidic (DxE) code directs concentration of cargo during export from the endoplasmic reticulum. J. Biol. Chem. 274:15937-15946.(PubMed).

Luan, P., Heine, A., Zeng, K., Moyer, B., Greasely, S.E., Kuhn, P., Balch, W.E., Wilson, I.A. (2000) A new functional domain of guanine nucleotide dissociation inhibitor (-GDI) involved in rab recycling. Traffic 1:270.(PubMed).

Allan, B.B., Moyer, B.D. and Balch, W.E. (2000) Rab1 recruitment of the effector p115 into a cis-SNARE complex programs budding COPII vesicles for fusion. Science, 289:444-448.(PubMed).

Alory, C and Balch, W.E. (2000) Molecular basis for rab prenylation. J. Cell Biol., 150:89-103.(PubMed).

Aridor, M. and Balch, W.E. (2000) Kinase signaling initiates COPII recruitment and export from the mammalian endoplasmic reticulum. J. Biol. Chem. 275:35673-35676.(PubMed).

Bannykh, S.I., Bannykh, G.I., Fish, K.N., Moyer, B.D., Riordan, J.R. and Balch, W.E. (2000) Traffic pattern of cystic fibrosis transmembrane regulator through the early exocytic pathway. Traffic 1(11):852-870. (PubMed).

Der, C.J. and Balch, W.E. (2000) GTPase traffic control. Nature 405(6788): 749, 751-752.(PubMed).

Allan, B.B., Weissman, J., Aridor, M., Moyer, B.D., Chen, C.D., Yoo, J.-S., and Balch, W.E. (2000) Stage-specific assays to study biosynthetic cargo selection and role of SNAREs in export from the endoplasmic reticulum and delivery to the Golgi. Methods 20 (4):411-416.(PubMed).

Moyer, B.D. and Balch, W.E. (2001). Structural basis for rab function - an overview. Methods in Enzymology, Academic Press Publishers, New York, NY, W.E. Balch, C. Der and A. Hall, Editors, 329:3-6.(PubMed).

Moyer, B.D., Matteson, J. and Balch, W.E. (2001). Expression of wild-type and mutant GFP-Rab1 for fluorescence microscopy analysis. Methods in Enzymology, Academic Press Publishers, New York, NY, W.E. Balch, C. Der and A. Hall, Editors, 329:6-14.(PubMed).

Beraud-Dufour, S. and Balch, W.E. (2001). Structural and functional organization of ARF proteins - an overview. Methods in Enzymology, Academic Press Publishers, New York, NY, W.E. Balch, C. Der and A. Hall, Editors,. 329:245-247. (PubMed).

Weissman, J.T., Aridor, M. and Balch, W.E. (2001). Purification and properties of rat liver Sec23-Sec24 complex. Methods in Enzymology, Academic Press Publishers, New York, NY, W.E. Balch, C. Der and A. Hall, Editors, 329: 431-438. (PubMed).

Moyer, B. D., Allan, B. B., and Balch, W. E. (2001). Rab1 interaction with a GM130 effector complex regulates COPII vesicle cis-Golgi tethering. Traffic 2(4), 268-76.(PubMed).

Aridor, M, Fish, K.N., Bannykh, S.I., Weissman, J. and Balch, W.E. (2001). The Sar1 GTPase coordinates biosynthetic cargo selection with endoplasmic reticulum export site assembly. J. Cell Biol. 152:213-229. (PubMed).

Weissman, J. T., Plutner, H., and Balch, W. E. (2001). The mammalian guanine nucleotide exchange factor mSec12 is essential for activation of the Sar1 GTPase directing endoplasmic reticulum export Traffic: 2(7)465-475.(PubMed).

Alory, C., and W.E. Balch. 2001. Organization of the Rab-GDI/CHM superfamily: the functional basis for choroideremia disease. Traffic. 2:532-543. (PubMed).

W. E. Balch, C. J. Der, A. Hall. Methods in Enzymology. J. A. Abelson, M. I. Simon, Eds., Regulators and effectors of small GTPases. Part E. GTPases involved in vesicular traffic (Academic Press, 2001), vol. 329.

W. E. Balch, C. J. Der, A. Hall. Methods in Enzymology. J. N. A. a. M. I. Simon, Ed., Regulators and effectors of small GTPases. Part G. Ras Family II (Academic Press, 2001), vol. 333.

Huang, M., J.T. Weissman, S. Beraud-Dufour, P. Luan, C. Wang, W. Chen, M. Aridor, I.A. Wilson, and W.E. Balch. (2001). Crystal structure of Sar1-GDP at 1.7 Å resolution and the role of the NH2-terminus in ER export. J Cell Biol. 155:937-948. (PubMed).

Chen, C.D., M.E. Huff, J. Matteson, L. Page, R. Phillips, J.W. Kelly, and W.E. Balch. 2001. Furin initiates gelsolin familial amyloidosis (FAF) in the golgi through a defect in Calcium stabilization. The Embo Journal. 20:6277-87. (PubMed).

Beraud-Dufour, S., and W.E. Balch. 2002. A journey through the exocytic pathway. J Cell Sci. 115:1779-80. (PubMed).

Huang, M., J.T. Weissman, C. Wang, W.E. Balch, and I.A. Wilson. 2002. Protein engineering for crystallization of the GTPase Sar1 that regulates ER vesicle budding. Acta Crystallogr. 58:700-3. (PubMed).

Nishimura, N., H. Plutner, K. Hahn and W.E. Balch. 2002. The delta-subunit of AP-3 is required for efficient transport of VSV-G from the trans golgi network (TGN) to the cell surface. Proc Natl Acad Sci U S A. 99(10):6755-60. (PubMed).

Sakisaka, T., T. Meerlo, J. Matteson, H. Plutner, and W.E. Balch. 2002. Rab-aGDI activity in neurotransmitter release is regulated by an Hsp90 chaperone complex. Embo J. 21:6125-6135. (PubMed).

Sawkar, A.R., W.-C. Cheng, E. Beutler, C.-H. Wong, W.E. Balch, and J.W. Kelly. 2002. Chemical chaperones increase the cellular activity of N370S b-glucosidase: A therapeutic strategy for Gaucher disease. Proc Natl Acad Sci U S A. 99:15428-15433.(PubMed)

Yoo, J.S., B.D. Moyer, S. Bannykh, H.M. Yoo, J.R. Riordan, and W.E. Balch. 2002. Non-conventional trafficking of the cystic fibrosis transmembrane conductance regulator through the early secretory pathway. J Biol Chem. 277:11401-9. (PubMed).

An, Y., Y. Shao, C. Alory, J. Matteson, T. Sakisaka, W. Chen, R.A. Gibbs, I.A. Wilson, and W.E. Balch. 2003. GDI-Rab GTPase recycling. Structure. 11:347-57.(PubMed).

Kelly, J.W., and W.E. Balch. 2003. Amyloid as a natural product. J Cell Biol. 161:461-462.(PubMed).

Huff, M.E., L. Page, W.E. Balch, and J.W. Kelly. 2003. Gelsolin domain 2 Ca2+ affinity determines susceptibility to furin proteolysis and familial amyloidosis of finnish type. J Mol Biol. 334:119-27.(PubMed).

Alory, C., and W.E. Balch. 2003. Molecular evolution of the Rab-escort-protein/guanine-nucleotide-dissociation-inhibitor superfamily. Mol Biol Cell. 14:3857-3867.(PubMed).

Huff, M. E., W. E. Balch, and J. W. Kelly. 2003. Pathological and functional amyloid formation orchestrated by the secretory pathway. Curr Opin Struct Biol 13:674-82.(PubMed).

Balch, W. E. 2004. Vesicle traffic in vitro. Cell 116:S17-9, 2 p following S19.(PubMed).

LaPointe, P., C. Gurkan, and W. E. Balch. 2004. Mise en place - this bud's for the Golgi. Mol Cell 14:413-414.(PubMed).

Page, L. J., M. E. Huff, J. W. Kelly, and W. E. Balch. 2004. Ca(2+) binding protects against gelsolin amyloidosis. Biochem Biophys Res Commun 322:1105-10. (PubMed).

	Selected Publications 1995-2008:
1.	Peter, F., Rowe, T., Nuoffer, C., Tisdale, E.J., Dascher, C., Schalk, E., Balch, W.E. (1995) Purification of His6-tagged Rab1 proteins using bacterial and insect cell expression systems, Expression and purification of mammalian Sar1a, Expression and purification of recombinant His6-tagged guanine nucleotide dissociation inhibitor and formation of Rab1 complex, Transient expression of small GTPases to study protein transport along secretory pathwa in vivo using recombinant T7 vaccinia virus system, Preparation of recombinant vaccinia virus for expression of small GTPases. In: Methods in Enzymology. Balch, W.E., Der, C., Hall, A. (Eds.). Academic Press, San Diego, p. 3, 49, 80, 165, 174.
2.	Balch, W.E. and Farquhar, M.G. (1995) Beyond bulk flow. Trends in Cell Biol. 5:16-19.
3.	Brown, W.J., Emr, S.D., Plutner , H. and Balch, W.E. (1995) Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells. J. Cell Biol. 130:781-796. (PubMed).
4.	Simpson, J.C., Dascher, C., Roberts, L.M., Lord, J.M. and Balch, W.E. (1995) Ricin cytotoxicity is sensitive to recycling between the endoplasmic reticulum and the Golgi complex. J. Biol. Chem. 270:20078-20083.(PubMed).
5.	Aridor, M., Bannykh, S.I., Rowe, T. and Balch, W.E. (1995) Sequential coupling between COPII and COPI vesicle coats in endoplasmic reticulum (ER) to Golgi transport. J. Cell Biol. 131:875-893. (PubMed).
6.	Schalk, I., Zeng, K., Wu, S.-K., Stura, E.A., Matteson, J., Huang, M., Tandon, A., Wilson, I.A. and Balch, W.E. (1995) Structure and mutational analysis of Rab GDP-dissociation inhibitor. Nature 381:42-48. (PubMed).
7.	Dascher, C. and Balch, W.E. (1996) Mammalian Sly1 regulates syntaxin 5 function in endoplasmic reticulum (ER) to Golgi transport. J. Biol. Chem. 271:15866-15869.(PubMed).
8.	Bannykh, S., Aridor, M., Plutner, H., Rowe, T. and Balch, W.E. (1995) Regulated export of cargo from the endoplasmic reticulum of mammalian cells. Cold Spring Harbor Lab. Press, 60:127. (PubMed).
9.	Aridor, M., Balch, W.E. (1996) Principles of selective transport: coat complexes hold the key. Trends Cell Biol. 6:315.
10.	Wu, S.-K., Zeng, K., Wilson, I.A., Balch, W.E. (1996) The GDI-CHM/REP connection: structural insights into the Rab GTPase cycle. Trends Biochem. Sci., 21:472-476. (PubMed).
11.	Tisdale, E.J. and Balch, W.E. (1996) Rab2 is essential for the assembly of pre-Golgi intermediates. J. Biol. Chem., 271:29372-29379.(PubMed).
12	Bannykh, S., Rowe, T. and Balch, W.E. (1996) The organization of endoplasmic reticulum export complexes. J. Cell Biol., 135:19-35. (PubMed).
13.	Traub, L.M. , S.I. Bannykh, J.E. Rodel, M. Aridor, W.E. Balch and Kornfeld, S. (1996) AP-2-containing clathrin coats assemble on mature lysosomes. J. Cell Biol. 135:1801-1814. (PubMed).
14.	Rowe, T., Aridor, M., McCaffery, J.M., Plutner, H. and Balch, W.E. (1996) COPII vesicles derived from mammalian endoplasmic reticulum (ER) microsomes recruit COPI. J. Cell Biol., 135:895-911.(PubMed).
15.	Aridor, M. and Balch, W.E. (1996) Timing is everything. Nature 383: 220-221.
16.	Tisdale, E.J., Plutner, H. Matteson, J., and Balch, W.E. (1997) p53/58: p53/58 binds COPI and is required for selective transport through the early secretory pathway. J. Cell Biol., 137:581-593.(PubMed).
17.	Turner, M.D., Plutner, H. and Balch, W.E. (1997) A rab GTPase is required for homotypic assembly of the endoplasmic reticulum. J. Biol. Chem., 272:13479-13483.(PubMed).
18.	Bannykh, S.I. and Balch, W.E. (1997) Membrane dynamics at the endoplasmic reticulum-Golgi interface. J Cell Biol., 138: 1-4.(PubMed).
19.	Nuoffer, C., S.K. Wu, Dascher, C. and Balch, W.E. (1997) MSS4 does not function as an exchange factor for Rab in endoplasmic reticulum to Golgi transport. Mol. Biol. Cell 8: 1305-1316. (PubMed).
20.	Rowe, T. and Balch, W.E. (1997) Membrane fusion. Bridging the gap by AAA ATPases. Nature 388: 20-21.(PubMed).
21.	Nishimura, N. and Balch, W.E. (1997) A di-acidic signal required for selective export from the endoplasmic reticulum. Science 277: 556-558.(PubMed).
22.	Bannykh, S.I., Nishimura, N. and Balch, W.E. (1998) Getting into the Golgi. Trends in Cell Biology 8:21-25.(PubMed).
23.	Rowe, T., Dascher, C., Bannykh, S.I, Plutner, H. and Balch, W.E. (1998) Role of vesicle-associated syntaxin 5 in the assembly of pre-Golgi intermediates. Science 279:696-700. (PubMed).
24.	Aridor, M., Weissman, J., Bannykh, S.I., Nuoffer, C. and Balch, W.E. (1998) Cargo selection by the COPII budding machinery during export from the endoplasmic reticulum. J. Cell Biol. 141:61-70. (PubMed).
25.	Bannykh, S.I., Balch, W.E. (1998) Selective transport of cargo between the endoplasmic reticulum and Golgi compartments. Histochem. 109:463-475.(PubMed).
26.	Tandon, A., Bannykh, S.I., Kowalchyk, J.A., Banerjee, A., Martin, T.F.J., Balch, W.E. (1998) Differential regulation of exocytosis by calcium and CAPS in semi-intact synaptosomes. Neuron 21:147-154.(PubMed).
27.	D'Adamo. P., Menegon, A., Lo Nigro, C., Grasso, M., Gulisano, M., Tamanini, F., Bienvenu, T., Gedeon, A.K., Oostra, B., Wu, S.K., Tandon, A., Valtorta, F., Balch, W.E., Chelly, J., Toniolo, D. (1998) Mutations in GDI1 are responsible for x-linked non-specific mental retardation. Nature Genetics 19:134-139.(PubMed).
28.	Wu, S.-K., Matteson, J., Zeng, K., Nishimura, N. and Balch, W.E. (1998) Molecular role for the rab binding pocket of guanine nucleotide dissociation inhibitor (GDI) in endoplasmic reticulum to Golgi transport. J. Biol. Chem. 273:26931-26938. (PubMed).
29.	Aridor, M., Bannykh, S.I., Rowe, T. and Balch, W.E. (1998) Cargo Can Modulate COPII Vesicle Formation from the Endoplasmic Reticulum. J. Biol. Chem., 274:4389-4399. (PubMed).
30.	Tandon, A., Tan, P.K., Bannykh, S.I., Banerjee, A. and Balch, W.E. (1998) Neurotransmitter release from semi-intact synaptosomes. Methods: A Companion to Methods in Enzymology 16:198.(PubMed).
31.	Luan, P., Balch, W.E., Emr, S.D. and Burd, C.G. (1998) Molecular Dissection of Guanine Nucleotide Dissociation Inhibitor Function in Vivo. J. Biol. Chem. 274:14806-14817.(PubMed).
32.	Allan, B.B. and Balch, W.E. (1998) In vitro analysis of endoplasmic reticulum to Golgi transport in mammalian cells. Current Protocols in Cell Biology, 11.3.1 — 11.3.22.
33.	Aridor, M. and Balch, W.E. (1999) Integration of endoplasmic reticulum signaling in health and disease. Nature Medicine 5:745-751.(PubMed).
34.	Allan, B.B. and Balch, W.E. (1999) Protein sorting by directed maturation of Golgi compartments. Science 285:63-66.(PubMed).
35.	Luan, P., Balch, W.E., Emr, S.D. and Burd, C.G. (1999) Molecular Dissection of Guanine Nucleotide Dissociation Inhibitor Function in Vivo. J. Biol. Chem. 274:14806-14817.(PubMed).
36.	Nishimura, N., Bannykh, S.I., Slabough, S., Matteson, J., Hahn, K. and Balch, W.E. (1999) A di-acidic (DxE) code directs concentration of cargo during export from the endoplasmic reticulum. J. Biol. Chem. 274:15937-15946.(PubMed).
37.	Luan, P., Heine, A., Zeng, K., Moyer, B., Greasely, S.E., Kuhn, P., Balch, W.E., Wilson, I.A. (2000) A new functional domain of guanine nucleotide dissociation inhibitor (-GDI) involved in rab recycling. Traffic 1:270.(PubMed).
38.	Allan, B.B., Moyer, B.D. and Balch, W.E. (2000) Rab1 recruitment of the effector p115 into a cis-SNARE complex programs budding COPII vesicles for fusion. Science, 289:444-448.(PubMed).
39.	Alory, C and Balch, W.E. (2000) Molecular basis for rab prenylation. J. Cell Biol., 150:89-103.(PubMed).
40.	Aridor, M. and Balch, W.E. (2000) Kinase signaling initiates COPII recruitment and export from the mammalian endoplasmic reticulum. J. Biol. Chem. 275:35673-35676.(PubMed).
41.	Bannykh, S.I., Bannykh, G.I., Fish, K.N., Moyer, B.D., Riordan, J.R. and Balch, W.E. (2000) Traffic pattern of cystic fibrosis transmembrane regulator through the early exocytic pathway. Traffic 1(11):852-870. (PubMed).
42.	Der, C.J. and Balch, W.E. (2000) GTPase traffic control. Nature 405(6788): 749, 751-752.(PubMed).
43.	Allan, B.B., Weissman, J., Aridor, M., Moyer, B.D., Chen, C.D., Yoo, J.-S., and Balch, W.E. (2000) Stage-specific assays to study biosynthetic cargo selection and role of SNAREs in export from the endoplasmic reticulum and delivery to the Golgi. Methods 20 (4):411-416.(PubMed).
44.	Moyer, B.D. and Balch, W.E. (2001). Structural basis for rab function - an overview. Methods in Enzymology, Academic Press Publishers, New York, NY, W.E. Balch, C. Der and A. Hall, Editors, 329:3-6.(PubMed).
45.	Moyer, B.D., Matteson, J. and Balch, W.E. (2001). Expression of wild-type and mutant GFP-Rab1 for fluorescence microscopy analysis. Methods in Enzymology, Academic Press Publishers, New York, NY, W.E. Balch, C. Der and A. Hall, Editors, 329:6-14.(PubMed).
46.	Beraud-Dufour, S. and Balch, W.E. (2001). Structural and functional organization of ARF proteins - an overview. Methods in Enzymology, Academic Press Publishers, New York, NY, W.E. Balch, C. Der and A. Hall, Editors,. 329:245-247. (PubMed).
47.	Weissman, J.T., Aridor, M. and Balch, W.E. (2001). Purification and properties of rat liver Sec23-Sec24 complex. Methods in Enzymology, Academic Press Publishers, New York, NY, W.E. Balch, C. Der and A. Hall, Editors, 329: 431-438. (PubMed).
48.	Moyer, B. D., Allan, B. B., and Balch, W. E. (2001). Rab1 interaction with a GM130 effector complex regulates COPII vesicle cis-Golgi tethering. Traffic 2(4), 268-76.(PubMed).
49.	Aridor, M, Fish, K.N., Bannykh, S.I., Weissman, J. and Balch, W.E. (2001). The Sar1 GTPase coordinates biosynthetic cargo selection with endoplasmic reticulum export site assembly. J. Cell Biol. 152:213-229. (PubMed).
50.	Weissman, J. T., Plutner, H., and Balch, W. E. (2001). The mammalian guanine nucleotide exchange factor mSec12 is essential for activation of the Sar1 GTPase directing endoplasmic reticulum export Traffic: 2(7)465-475.(PubMed).
51.	Alory, C., and W.E. Balch. 2001. Organization of the Rab-GDI/CHM superfamily: the functional basis for choroideremia disease. Traffic. 2:532-543. (PubMed).
52.	W. E. Balch, C. J. Der, A. Hall. Methods in Enzymology. J. A. Abelson, M. I. Simon, Eds., Regulators and effectors of small GTPases. Part E. GTPases involved in vesicular traffic (Academic Press, 2001), vol. 329.
53.	W. E. Balch, C. J. Der, A. Hall. Methods in Enzymology. J. N. A. a. M. I. Simon, Ed., Regulators and effectors of small GTPases. Part G. Ras Family II (Academic Press, 2001), vol. 333.
54.	Huang, M., J.T. Weissman, S. Beraud-Dufour, P. Luan, C. Wang, W. Chen, M. Aridor, I.A. Wilson, and W.E. Balch. (2001). Crystal structure of Sar1-GDP at 1.7 Å resolution and the role of the NH2-terminus in ER export. J Cell Biol. 155:937-948. (PubMed).
55.	Chen, C.D., M.E. Huff, J. Matteson, L. Page, R. Phillips, J.W. Kelly, and W.E. Balch. 2001. Furin initiates gelsolin familial amyloidosis (FAF) in the golgi through a defect in Calcium stabilization. The Embo Journal. 20:6277-87. (PubMed).
56.	Beraud-Dufour, S., and W.E. Balch. 2002. A journey through the exocytic pathway. J Cell Sci. 115:1779-80. (PubMed).
57.	Huang, M., J.T. Weissman, C. Wang, W.E. Balch, and I.A. Wilson. 2002. Protein engineering for crystallization of the GTPase Sar1 that regulates ER vesicle budding. Acta Crystallogr. 58:700-3. (PubMed).
58.	Nishimura, N., H. Plutner, K. Hahn and W.E. Balch. 2002. The delta-subunit of AP-3 is required for efficient transport of VSV-G from the trans golgi network (TGN) to the cell surface. Proc Natl Acad Sci U S A. 99(10):6755-60. (PubMed).
59.	Sakisaka, T., T. Meerlo, J. Matteson, H. Plutner, and W.E. Balch. 2002. Rab-aGDI activity in neurotransmitter release is regulated by an Hsp90 chaperone complex. Embo J. 21:6125-6135. (PubMed).
60.	Sawkar, A.R., W.-C. Cheng, E. Beutler, C.-H. Wong, W.E. Balch, and J.W. Kelly. 2002. Chemical chaperones increase the cellular activity of N370S b-glucosidase: A therapeutic strategy for Gaucher disease. Proc Natl Acad Sci U S A. 99:15428-15433.(PubMed)
61.	Yoo, J.S., B.D. Moyer, S. Bannykh, H.M. Yoo, J.R. Riordan, and W.E. Balch. 2002. Non-conventional trafficking of the cystic fibrosis transmembrane conductance regulator through the early secretory pathway. J Biol Chem. 277:11401-9. (PubMed).
62.	An, Y., Y. Shao, C. Alory, J. Matteson, T. Sakisaka, W. Chen, R.A. Gibbs, I.A. Wilson, and W.E. Balch. 2003. GDI-Rab GTPase recycling. Structure. 11:347-57.(PubMed).
63.	Kelly, J.W., and W.E. Balch. 2003. Amyloid as a natural product. J Cell Biol. 161:461-462.(PubMed).
64.	Huff, M.E., L. Page, W.E. Balch, and J.W. Kelly. 2003. Gelsolin domain 2 Ca2+ affinity determines susceptibility to furin proteolysis and familial amyloidosis of finnish type. J Mol Biol. 334:119-27.(PubMed).
65.	Alory, C., and W.E. Balch. 2003. Molecular evolution of the Rab-escort-protein/guanine-nucleotide-dissociation-inhibitor superfamily. Mol Biol Cell. 14:3857-3867.(PubMed).
66.	Huff, M. E., W. E. Balch, and J. W. Kelly. 2003. Pathological and functional amyloid formation orchestrated by the secretory pathway. Curr Opin Struct Biol 13:674-82.(PubMed).
67.	Balch, W. E. 2004. Vesicle traffic in vitro. Cell 116:S17-9, 2 p following S19.(PubMed).
68.	LaPointe, P., C. Gurkan, and W. E. Balch. 2004. Mise en place - this bud's for the Golgi. Mol Cell 14:413-414.(PubMed).
69.	Page, L. J., M. E. Huff, J. W. Kelly, and W. E. Balch. 2004. Ca(2+) binding protects against gelsolin amyloidosis. Biochem Biophys Res Commun 322:1105-10. (PubMed).
70.	Wang, X., J. Matteson, Y. An, B. D. Moyer, J. S. Yoo, S. Bannykh, I. A. Wilson, J. R. Riordan, and W. E. Balch. 2004. COPII-dependent export of cystic fibrosis transmembrane conductance regulator (CFTR) from the ER utilizes a di-acidic exit code. J Cell Biol 167:65-74. (PubMed).
71.	Chen, C.Y., Sakisaka, T. and Balch, W.E. (2005) Use of Hsp90 inhibitors to disrupt GDI-dependent Rab recycling. Methods Enzymol, 403, 339-347.(PubMed).
72.	LaPointe, P. and Balch, W.E. (2005) Purification and properties of mammalian Sec23/24 from insect cells. Methods Enzymol, 404, 66-74. (PubMed).
73.	Gurkan, C. and Balch, W.E. (2005) Recombinant production in baculovirus-infected insect cells and purification of the mammalian Sec13/Sec31 complex. Methods Enzymol, 404, 58-66. (PubMed).
74.	Wiseman, R. L., and W. E. Balch. 2005. A new pharmacology - drugging stressed folding pathways. Trends Mol Med.PMID: 16005683. (PubMed).
75.	Gurkan, C., H. Lapp, C. Alory, A. I. Su, J. B. Hogenesch, and W. E. Balch. 2005. Large-Scale Profiling of Rab GTPase Trafficking Networks: The Membrome. Mol Biol Cell 16:3847-64. (PubMed).
76.	Sekijima, Y., R. L. Wiseman, J. Matteson, P. Hammarstrom, S. R. Miller, A. R. Sawkar, W. E. Balch, and J. W. Kelly. 2005. The biological and chemical basis for tissue-selective amyloid disease. Cell 121:73-85.(PubMed).
77.	Fowler, D.M., Koulov, A.V., Alory-Jost, C., Marks, M.S., Balch, W.E. and Kelly, J.W. (2006) Functional Amyloid Formation within Mammalian Tissue. PLoS Biol, 4, e6.(PubMed).
78.	Page, L.J., Suk, J.Y., Huff, M.E., Lim, H.J., Venable, J., Yates, J., Kelly, J.W. and Balch, W.E. (2005) Metalloendoprotease cleavage triggers gelsolin amyloidogenesis. Embo J, 24, 4124-4132.(PubMed).
79.	Bannykh, S.I., Plutner, H., Matteson, J. and Balch, W.E. (2005) The Role of ARF1 and Rab GTPases in Polarization of the Golgi Stack. Traffic, 6, 803-819.(PubMed).
80.	Wiseman, R.L. and Balch, W.E. (2005) A new pharmacology - drugging stressed folding pathways. Trends Mol Med, 11, 347-350. (PubMed).
81.	Stagg, S.M., Gurkan, C., Fowler, D.M., LaPointe, P., Foss, T.R., Potter, C.S., Carragher, B. and Balch, W.E. (2006) Structure of the Sec13/31 COPII coat cage. Nature, 439, 234-238. (PubMed).
82.	Suk, J.Y., Zhang, F., Balch, W.E., Linhardt, R.J. and Kelly, J.W. (2006) Heparin Accelerates Gelsolin Amyloidogenesis. Biochemistry, 45, 2234-2242. (PubMed).
83.	Chen, C.Y. and Balch, W.E. (2006) The Hsp90 Chaperone Complex Regulates GDI-dependent Rab Recycling. Mol Biol Cell. 17:3494-507. (PubMed).
84.	Kelly, J.W. and Balch, W.E. (2006) The integration of cell and chemical biology in protein folding. Nat Chem Biol, 2, 224-227. (PubMed).
85.	Gurkan, C., S.M. Stagg, P. Lapointe, and W.E. Balch. (2006). The COPII cage: unifying principles of vesicle coat assembly. Nat Rev Mol Cell Biol. 7:727-38. (PubMed).
85.	Wang, X., J. Venable, P. Lapointe, D.M. Hutt, A.V. Koulov, J. Coppinger, C. Gurkan, W. Kellner, J. Matteson, H. Plutner, J.R. Riordan, J.W. Kelly, J.R. Yates, 3rd, and W.E. Balch. 2006. Hsp90 Cochaperone Aha1 Downregulation Rescues Misfolding of CFTR in Cystic Fibrosis. Cell. 127:803-815.(PubMed).
86.	Sawkar, A.R., M. Schmitz, K.P. Zimmer, D. Reczek, T. Edmunds, W.E. Balch, and J.W. Kelly. 2006. Chemical chaperones and permissive temperatures alter localization of Gaucher disease associated glucocerebrosidase variants. ACS Chem Biol. 1:235-51.(PubMed).
87.	Cui, L., L. Aleksandrov, X.B. Chang, Y.X. Hou, L. He, T. Hegedus, M. Gentzsch, A. Aleksandrov, W.E. Balch, and J.R. Riordan. 2007. Domain interdependence in the biosynthetic assembly of CFTR. J Mol Biol. 365:981-94.(PubMed)
88.	Stagg, S.M., P. Lapointe, and W.E. Balch. 2007. Structural design of cage and coat scaffolds that direct membrane traffic. Curr Opin Struct Biol. 17:221-8.(PubMed).
89.	Fowler, D.M., A.V. Koulov, W.E. Balch, and J.W. Kelly. 2007. Functional amyloid - from bacteria to humans. Trends Biochem Sci. 32:217-224.(Pub.Med).
90.	Wiseman, R.L., A. Koulov, E. Powers, J.W. Kelly, and W.E. Balch. 2007. Protein energetics in maturation of the early secretory pathway. Curr Opin Cell Biol. 19:359-67.(Pub.Med)
91.	Wiseman, R.L., E.T. Powers, J.N. Buxbaum, J.W. Kelly, and W.E. Balch. 2007. An adaptable standard for protein export from the endoplasmic reticulum. Cell. 131:809-21.(PubMed).
92.	Gurkan, C., A.V. Koulov, and W.E. Balch. 2007. An evolutionary perspective on eukaryotic membrane trafficking. Adv. Exp. Med. Biol. 607:73-83.(PubMed).
93.	Hutt, D.M., and W.E. Balch. 2008. Rab1b silencing using small interfering RNA for analysis of disease-specific function. Methods Enzymol. 438:1-10.(PubMed).
94.	Brown, W.J., H. Plutner, D. Drecktrah, B.L. Judson, and W.E. Balch. 2008. The lysophospholipid acyltransferase antagonist CI-976 inhibits a late step in COPII vesicle budding. Traffic (Copenhagen, Denmark). 9:786-97.(PubMed).
95.	Balch, W.E., R.I. Morimoto, A. Dillin, and J.W. Kelly. 2008. Adapting proteostasis for disease intervention. Science. 319:916-9. (PubMed).