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Wednesday, April 3

4:00 PM - 5:00 PM

Title: The Artificial Leaf
Speaker: Daniel G. Nocera, Ph.D., Harvard University, Department of Chemistry and Chemical Biology
Sponsor: Chemistry Distinguished Lecture Series
Location: Valerie Timken Amphitheater, Green Hospital

Thursday, April 4

12:00 PM - 1:00 PM

Title: Signaling and Specificity of Positive Selection of CD4+ T cells
Speaker: Paul Allen, Ph.D., Department of Microbiology and Immunology, Washington University, St. Louis
Sponsor: Immunology Affinity Group
Location: MBB2N - THE COMMITTEE Lecture Hall

3:30 PM - 4:30 PM

Title: Deciphering Structural Bases of Cellular Function by CryoEM: Act I. Microtubule Dynamic Instability - Act II. Proteasomal Degradation
Speaker: Gabriel Lander, Ph.D., Department of Integrative Structural and Computational Biology, The Scripps Research Institute
Host: Ian Wilson, Ph.D.
Sponsor: Structure and Computation Affinity Group & DISCoBio
Location: BCC1 - W.M. Keck Foundation Amphitheater

5:30 PM - 7:00 PM

Title: Personalized Medicine: Road to New Opportunities
Speakers:

• Rob Bookstein, M.D., Director, Corporate and Venture Development at Illumina
• James Christensen, Ph.D., Director, Translational Pharmacology at Pfizer
• Michael Jackson, Ph.D., Vice President, Drug Discovery and Development, Sanford Burnham
• Ashley Van Zeeland, Ph.D., MBA, Co-Founder and CEO of Cypher Genomics
• Paul Billings, M.D., Ph.D., Chief Medical Officer of Life Technologies
• Rita Lim-Wilby, Corporate Development, Research Outsourcing, Founder of PGC200

Sponsor: Oxbridge Biotech Roundtable
Location: BCC1 - W.M. Keck Foundation Amphitheater
Notes:

Light refreshments will be provided.

For more details on the event go to: http://www.oxbridgebiotech.com/events/personalizedmedicine/

Friday, April 5

2:00 PM - 3:00 PM

Title: New Synthetic Transformations Using Alkenes: From Transition-Metal Catalysis to Metal-Free Radical Reactions
Speaker: Erik J. Alexanian, Ph.D., Department of Chemistry, The University of North Carolina at Chapel Hill
Host: Phil Baran, Ph.D., and Ryan Shenvi Ph.D.
Sponsor: Chemistry Lecture Series
Location: BCC1 - W.M. Keck Foundation Amphitheater

2:00 PM - 3:00 PM

Title: Inositol (1,4,5) Trisphosphate 3-kinase B (ItpkB) is Central toThymic Development by Regulating Phosphoinositide 3-kinases (PI3K) Downstream of Mild and Strong TCR Signals
Speaker: Luise Sternberg, Doctorate of Philosophy Thesis Presentation
Advisor: Associate Professor Karsten Sauer, Ph.D.
Sponsor: Kellogg School of Science and Technology
Location: MBB2N - THE COMMITTEE Lecture Hall
Notes: A Reception will be held at 1:30 pm in the Graduate Student Lounge, The Arnold and Mabel Beckman Center for Chemical Sciences.

Wednesday, April 10

5:00 PM - 6:00 PM

Title: Mechanism of Action of Novel Insulin Sensitizers
Speaker: Patrick Griffin, Ph.D., The Scripps Research Institute, Jupiter, Florida
Sponsor: Faculty Lecture Series
Location: Valerie Timken Amphitheater, Green Hospital

Thursday, April 11

3:30 PM - 4:30 PM

Title: How Flies Fly: Myosin Function, Folding and Disease in Skeletal and Cardiac Muscles
Speaker: Sanford I. Bernstein, Ph.D., Professor, Department of Biology, San Diego State University, San Diego
Host: Claudio Joazeiro, Ph.D., and Velia Fowler, Ph.D.
Sponsor: MCBAG Seminar
Location: BCC1 - W.M. Keck Foundation Amphitheater

Friday, April 12

4:00 PM - 5:00 PM

Title: From Conventional Ligands to Engineered Enzymes - Rh(III) Catalysis for C-H Activation
Speaker: Tomislav Rovis, Ph.D., Department of Chemistry, Colorado State University
Host: Ryan Shenvi, Ph.D.
Sponsor: Chemistry Lecture Series
Location: BCC1 - W.M. Keck Foundation Amphitheater

Monday, April 15

2:00 PM - 3:00 PM

Title: Multi-Step One-Pot Transformations Starting from Easily Accessible Substances
Speaker: Masahiro Murakami, Ph.D., Professor, Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Japan
Host: Jin-Quan Yu, Ph.D.
Sponsor: Chemistry Lecture Series
Location: BCC1 - W.M. Keck Foundation Amphitheater

Thursday, April 18

12:00 PM - 1:00 PM

Title: Microbiota-Mediated Defense Against Intestinal Infection
Speaker: Eric G. Pamer, M.D., Investigator, Memorial Sloan-Kettering Cancer Center
Sponsor: Immunology Affinity Group
Location: MBB2N - THE COMMITTEE Lecture Hall

Thursday, April 25

12:00 PM - 1:00 PM

Title: Antigen Receptor Locus Diversification, Genome Stability and Cancer in the Immune System
Speaker: Frederick Alt, Ph.D., Professor of Genetics and Medicine, Harvard Medical School
Sponsor: Immunology Affinity Group
Location: MBB2N - THE COMMITTEE Lecture Hall

Friday, April 26

2:00 PM - 3:00 PM

Title: Signal Amplification: Applications in Diagnostics and Responsive Materials
Speaker: Scott Phillips, Ph.D., Department of Chemistry, Pennsylvania State University
Host: Dale Boger, Ph.D.
Sponsor: Chemistry Lecture Series
Location: BCC1 - W.M. Keck Foundation Amphitheater

Monday, April 29

4:00 PM - 5:00 PM

Title: Aging and Rejuvenation in C. elegans
Speaker: Cynthia Kenyon, Ph.D., American Cancer Society Professor, Department of Biochemistry and Biophysics Director, Larry L. Hillblom Center for the Biology of Aging, University of California, San Francisco
Sponsor: The Kellogg School of Science and Technology Graduate Program in Biology Distinguished Lecturer Series
Location: Valerie Timken Amphitheater, Green Hospital

Tuesday, April 30

10:00 AM - 11:00 AM

Title: Mass Spectrometry in Neurobiology Discovery
Speaker: John Yates, III, Ph.D., Professor - Department of Chemical Physiology, The Scripps Research Institute
Host: Anton Maximov, Ph.D.
Sponsor: DNC Neuroscience Seminar
Location: DNC Auditorium, 3528 General Atomics Court

2:00 PM - 3:00 PM

Title: Synthesis and Evolution of Natural Product-Like Macrocycles for Selective Biomolecular Recognition
Speaker: Rudi Fasan, Ph.D., Department of Chemistry, University of Rochester
Host: Phil Baran, Ph.D.
Sponsor: Chemistry Lecture Series
Location: BCC1 - W.M. Keck Foundation Amphitheater

Thursday, May 2

4:00 PM - 5:00 PM

Title: The Hexadehydro-Diels-Alder Reaction
Speaker: Thomas R. Hoye, Ph.D., Merck Professor of Chemistry, Department of Chemistry, University of Minnesota - Twin Cities
Sponsor: Chemistry Distinguished Lecture Series
Location: Valerie Timken Amphitheater, Green Hospital

Friday, May 3

12:00 PM - 5:00 PM

Title: J. Gregor Sutcliffe Retirement Symposium
Speakers:

• John Elder, Ph.D., The Scripps Research Institute, La Jolla, CA
• Floyd Bloom, M.D., The Scripps Research Institute, La Jolla, CA
• George Koob, Ph.D., The Scripps Research Institute, La Jolla, CA

Location: MBB2N - THE COMMITTEE Lecture Hall
Notes: Speakers will also include many past Post-Doctoral Trainees.

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BCC - The Beckman Center for Chemical Sciences
GHB - Green Hospital Building
IMM - Immunology Building
MBB - The Skaggs Institute for Chemical Biology
SRC - Stein Research Center
MEM - Molecular and Experimental Medicine Building

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For more information contact:
calendar@scripps.edu

Scientific seminar announcements and reminders should be sent to seminars@scripps.edu