2007

Zhou, T., L. Xu, B. Dey, A.J. Hessell, D. Van Ryk, S-H. Xiang, X. Yang, M-Y. Zhang, M.B. Zwick, J. Arthos, D.R. Burton , D.S. Dimitrov, J. Sodroski, R. Wyatt, G.J. Nabel, P. D. Kwong. Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature, 445 :732-737, 2007.

Nelson, J.D., F.M. Brunel, R. Jensen, E.T. Crooks, R.M.F. Cardoso, M. Wang, A. Hessell, I.A. Wilson, J.M. Binley, P.E. Dawson, D.R. Burton , M.B. Zwick. In vitro affinity maturation of Z13, a broadly neutralizing antibody against human immunodeficiency virus type 1 (HIV-1) gp41. J. Virol. 81:4033-4043, 2007.

Pantophlet, R., R.O. Aguilar-Sino, T. Wrin, L.A. Cavacini, D.R. Burton . Analysis of the neutralization breadth of the anti-V3 antibody F425-B4e8 and re-assessment of its epitope fine specificity by scanning mutagenesis. Virology, 364: 441-453, 2007.

Dhillon, A.K., H. Donners, R. Pantophlet, W.E. Johnson, J.M. Decker, G.M. Shaw, F-H. Lee, D.D. Richman, R.W. Doms, G. Vanham, D.R. Burton . Dissecting the neutralizing antibody specificities of broadly neutralizing sera from HIV-1 infected donors. J. Virol. , 81: 6548-6562, 2007.

Crooks, E.T., P.L. Moore, M. Franti, C.S. Cayanan, P. Zhu, P. Jiang, R. deVries, C. Wiley, I. Zharkikh, N. Sch ülke, K.H. Roux, D.C. Montefiori, D.R. Burton , J.M. Binley. A Comparative Immunogenicity Study of HIV-1 Virus-Like Particles Bearing Various Forms of Envelope Proteins, Particles Bearing no Envelope and soluble monomeric gp120. Virology, 366 :245-262, 2007.

Law, M., R.M.F. Cardoso, I.A. Wilson, D.R. Burton . Antigenic and immunogenic study of membrane-proximal external region-grafted gp120 antigens by a DNA prime-protein boost immunization strategy. J. Virol., 81: 4272-4285, 2007.

Oswald W.B., T.W. Geisbert, K.J. Davis, J.B. Geisbert, N.J. Sullivan, P.B. Jahrling, P.W.H.I. Parren, D.R. Burton . Neutralizing antibody fails to impact the course of Ebola virus infection in monkeys, PLoS Pathogens , 3 :62-66 2007.

Bowley, D.R., A.F. Labrijn, M.B. Zwick, D.R. Burton . Antigen selection from an HIV-1 immune antibody library displayed on yeast yields many novel antibodies compared to selection from the same library displayed on phage, Protein Engineering Design & Selection (PEDS) , 20: 81-90, 2007.

Scanlan, C.N., G.E. Ritchie, K. Baruah, D. Harvey, B.B. Singer, L. Lucka, M.D. Crispin, M.R. Wormald, P. Wentworth, Jr., N. Zitzmann, P.M. Rudd, D.R. Burton , R.A. Dwek. Inhibition of mammalian glycan biosynthesis produces non-self antigens for a broadly neutralizing, HIV-1 specific antibody. J. Mol. Biol. , 372 :16-22, 2007.

Mantis, N.J., A.J. Hessell, J. Palaia, S. Mahta, Z. Zhu, B. Corthesy, M.R. Neutra, D.R. Burton , E.N. Janoff. Inhibition of HIV-1 infectivity and epithelial cell transfer by a recombinant human IgA to envelope gp120. J. Immunology, 179: 3144-315 2 , 2007.

Hessell, A.J., L. Hangartner, M. Hunter, C.E.G. Havenith, F.J. Beurskens, J.M. Bakker, C.M.S. Lanigan, G. Landucci, D.N. Fothal, P.W.H.I. Parren, P.A. Marx, D.R. Burton . The Fc receptor but not complement binding is important in antibody protection against HIV. Nature , 449: 101-104, 2007.

Scherer, E.M., M.B. Zwick, L. Teyton, D.R. Burton . Difficulties in eliciting broadly neutralizing anti-HIV antibodies are not explained by cardiolipin autoreactivity. AIDS , 21 :2131-2139, 2007.

Burton, D.R. , I.A. Wilson. Square dancing antibodies. Science , 317: 1507-1508, 2007.

Law, M., T. Maruyama, J. Lewis, E. Giang, A.W. Tarr, Z. Stamataki, P. Gastaminza, F.V. Chisari, I.M. Jones, R.I. Fox, J.K. Ball, J.A. McKeating, N.M. Kneteman, D.R. Burton . Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge. Nature Medicine, 14: 26-27, 2007.

Zwick, M.B., Burton, D.R. HIV-1 neutralization: mechanisms and relevance to vaccine design. Current HIV Research , 5 :608-624, 2007.