2010
Cai, G., Imasaki, T., Yamada, K., Cardelli, F., Takagi, Y. and F.J. Asturias 2010. Mediator Head module Structure and Functional Interactions
Nat Struct Mol Biol In press.
2009
Cai, G., Imasaki, T., Takagi, Y. and F.J. Asturias 2009. Mediator structural conservation and implications for the regulation mechanism
Structure 17:559-567.
Brignole, E.J., Smith, S., and F.J. Asturias 2009. Conformational Flexibility of Metazoan Fatty Acid Synthase Enables Catalysis
Nat Struct Mol Biol 16:190-197
Asturias F.J. 2009. TFIID: A closer look highlights its complexity
Structure 17:1323-1324.
2008
Chaban, Y.L., Ezeokonkwo, C., Chung, W.H., Zhang, F., Kornberg, R.D., Maier-Davis, B., Lorch, Y., and F.J. Asturias 2008. Structure of a RSC-Nucleosome Complex and Insights into Chromatin Remodeling
Nat Struct Mol Biol 15:1272-1277.
Fuxreiter, M., Tompa, P., Simon, I., Uversky, V.N., Hansen, J.C., and F.J. Asturias 2008. Malleable machines take shape in eukaryotic transcriptional regulation
Nat Chem Biol 4:728-737.
Shaikh, T.R., Gao, H., Baxter, W.T., Asturias, F.J., Boisset, N., Leith, A., and J. Frank 2008. SPIDER Image Processing for Single-Particle Reconstruction of Biological Macromolecules from Electron Micrographs
Nat Protocols 3:1941-1974.
Yang, C., Penczek, P., Leith, A., Asturias, F., J., Ng, E. G., Glaeser, R. M., and J. Frank 2008. The Parallelization of SPIDER on Distributed-Memory Computers Using MPI.
J Struct Biol 157:240-249.
2006
Takagi Y., Guillermo C., Komori H., Brown J.A., Ehrensberger A.H., Hudmon A., Asturias F.J., and R.D. Kornberg 2006. Head Module Control of Mediator Interactions
Mol Cell 23:355-364.
Asturias, F.J., Cheung, I., Sabouri, N., Chilkova, O., Wepplo, D., and E. Johansson 2006. Structure of Saccharomyces cerevisiae DNA polymerase epsilon by cryo-electron microscopy
Nat Struct Mol Biol 13:35-43.
Asturias, F. J. 2006. Mammalian Fatty Acid Synthase: X-ray Structure of a Molecular Assembly Line
ACS Chem Biol 1:135-138.
2005
Takagi, Y., Chadick, J.Z., Davis, J.A., and F.J. Asturias 2005. Preponderance of free Mediator in the yeast Saccharomyces cerevisiae
J Biol Chem. 280:31200-31207.
Chadick, J. Z. and F.J. Asturias 2005. Structure of eukaryotic Mediator complexes
Trends in Biochem Sci. 30:264-271.
Asturias, F. J., Chadick, J. Z., Cheung, I. K., Stark, H., Witkowski, A., Joshi, A. K. and S. Smith 2005. Structure and molecular organization of mammalian fatty acid synthase
Nat Struct Mol Biol. 12:225-232.
2004
F.J. Asturias 2004. RNA polymerase II structure, and organization of the preinitiation complex
Curr Opin Struct Biol. 14:121-129.
Bourbon, H.M., et al. 2004. A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II
Mol Cell. 14:553-557.
Witkowski, A., Ghosal, A., Joshi, A. K., Witkowska, H. E., Asturias, F. J. and S. Smith 2004. Head-to-head coiled arrangement of the subunits of the animal fatty acid synthase
Chem Biol. 11:1667-1676.
F.J. Asturias 2004. Another piece in the transcription initation puzzle
Nat Struct Mol Biol. 11:1031-1033.
2003
Asturias, F.J., and J.L. Craighead 2003. RNA polymerase II at initiation
PNAS. 100:6893-6895.
Chung, W.H., Craighead, J.L., Chang, W.H., Ezeokonkwo, C., Bareket-Samish, A., Kornberg, R.D., and F.J. Asturias 2003. RNA Polymerase II/TFIIF Structure and Conserved Organization of the Initiation Complex
Mol Cell. 12:1003-1013.
2002
Asturias, F. J., Ezeokonkwo, C., Kornberg, R. D. and Y. Lorch 2002. Electron microscopic analysis of the RSC chromatin remodeling complex
Meth Enzymol. 376:48-62.
Asturias, F. J., Chung, W. H., Kornberg, R. D. and Y. Lorch 2002. Structural analysis of the RSC chromatin-remodeling complex
PNAS. 99:13477-13480.
Joshua A. Davis, Yuichiro Takagi, Roger D. Kornberg, and F. J. Asturias 2002. Structure of the yeast RNA polymerase II holoenzyme: Mediator conformation and polymerase interaction
Mol Cell. 10:409-415.
Craighead, J., Chang, W. and F.J. Asturias 2002. Structure of Yeast RNA Polymerase II in Solution. Implications for Enzyme Regulation and Interaction with Promoter DNA
Structure (Camb). 10:1117-1125.
2000
Dotson, M. R., Yuan, C. X., Roeder, R. G., Myers, L. C., Gustafsson, C. M., Jiang, Y. W., Li, Y., Kornberg, R. D. and F.J. Asturias 2000. Structural organization of yeast and mammalian mediator complexes
PNAS. 97:14307-14310.
1999
Asturias, F.J., Y.W. Jiang, L.C. Myers, C.M. Gustafsson and R.D. Kornberg 1999. Conserved structures of mediator and RNA polymerase II holoenzyme
Science. 283:985-987.
Asturias, F.J. and R.D. Kornberg. 1999. Protein crystallization on lipid layers and structure determination of the RNA polymerase II transcription initiation complex
J. Biol. Chem.. 274:6813-6816.
1997
Asturias F.J., W. Chang, Y. Li and R.D. Kornberg. 1997. Electron cyrstallography of yeast RNA polymerase II preserved in vitreous ice
Ultramicroscopy. 70:133-143.
Asturias, F.J., G.D. Meredith, C.L. Poglitsch and R.D. Kornberg. 1997. Two conformations of RNA polymerase I I revealed by electron crystallography
J. Mol. Biol. 272:536-540.
